| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSPPYP00000016218 | GEM | ENSPPYP00000016218 | ENSPPYP00000021031 | annotation not available | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | 0.498 |
| GEM | ENSPPYP00000016218 | ENSPPYP00000021031 | ENSPPYP00000016218 | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | annotation not available | 0.498 |
| GEM | ITSN1 | ENSPPYP00000021031 | ENSPPYP00000012707 | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | ITSN1 isoform 4. | 0.689 |
| GEM | ITSN2 | ENSPPYP00000021031 | ENSPPYP00000014069 | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | ITSN2 isoform 3. | 0.815 |
| GEM | KALRN | ENSPPYP00000021031 | ENSPPYP00000015063 | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | KALRN isoform 1. | 0.498 |
| GEM | KIF9 | ENSPPYP00000021031 | ENSPPYP00000015573 | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.721 |
| GEM | MET | ENSPPYP00000021031 | ENSPPYP00000020106 | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.569 |
| GEM | MST1R | ENSPPYP00000021031 | ENSPPYP00000015506 | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | MST1R isoform 1. | 0.569 |
| GEM | MYO9A | ENSPPYP00000021031 | ENSPPYP00000007495 | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | MYO9A isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.509 |
| GEM | MYO9B | ENSPPYP00000021031 | ENSPPYP00000010871 | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | MYO9B isoform 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.509 |
| GEM | TRIO | ENSPPYP00000021031 | ENSPPYP00000017147 | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | TRIO isoform 3. | 0.498 |
| ITSN1 | GEM | ENSPPYP00000012707 | ENSPPYP00000021031 | ITSN1 isoform 4. | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | 0.689 |
| ITSN1 | ITSN2 | ENSPPYP00000012707 | ENSPPYP00000014069 | ITSN1 isoform 4. | ITSN2 isoform 3. | 0.918 |
| ITSN2 | GEM | ENSPPYP00000014069 | ENSPPYP00000021031 | ITSN2 isoform 3. | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | 0.815 |
| ITSN2 | ITSN1 | ENSPPYP00000014069 | ENSPPYP00000012707 | ITSN2 isoform 3. | ITSN1 isoform 4. | 0.918 |
| ITSN2 | MET | ENSPPYP00000014069 | ENSPPYP00000020106 | ITSN2 isoform 3. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.677 |
| ITSN2 | MST1R | ENSPPYP00000014069 | ENSPPYP00000015506 | ITSN2 isoform 3. | MST1R isoform 1. | 0.677 |
| KALRN | GEM | ENSPPYP00000015063 | ENSPPYP00000021031 | KALRN isoform 1. | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | 0.498 |
| KIF9 | GEM | ENSPPYP00000015573 | ENSPPYP00000021031 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | 0.721 |
| MET | GEM | ENSPPYP00000020106 | ENSPPYP00000021031 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | GTP-binding protein GEM; Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity (By similarity); Belongs to the small GTPase superfamily. RGK family. | 0.569 |