STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EXT1Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). (746 aa)    
Predicted Functional Partners:
EXT2
Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.
    
0.999
EXTL2
Exostosin like glycosyltransferase 2.
    
0.823
SNX19
SNX19 isoform 1.
      
 0.781
CHRNA1
CHRNA1 isoform 1.
   
  
 0.743
CHAD
CHAD isoform 1.
   
  
 0.688
TRPS1
TRPS1 isoform 3.
      
 0.688
TBX5
T-box transcription factor 5.
   
  
 0.686
NDST1
N-deacetylase and N-sulfotransferase 1.
   
  
 0.685
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 
 0.592
BBS9
BBS9 isoform 2.
      
 0.584
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (22%) [HD]