| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABAT | ACSS1 | ENSPPYP00000008008 | ENSPPYP00000012045 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyl-coenzyme A synthetase. | 0.863 |
| ABAT | ACSS2 | ENSPPYP00000008008 | ENSPPYP00000012219 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | ACSS2 isoform 8. | 0.848 |
| ABAT | AGXT2 | ENSPPYP00000008008 | ENSPPYP00000017192 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.938 |
| ABAT | ALDH1B1 | ENSPPYP00000008008 | ENSPPYP00000021352 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | 0.944 |
| ABAT | ALDH2 | ENSPPYP00000008008 | ENSPPYP00000005665 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aldehyde dehydrogenase, mitochondrial; Is capable of converting retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family. | 0.944 |
| ABAT | ALDH6A1 | ENSPPYP00000008008 | ENSPPYP00000006799 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aldehyde dehydrogenase 6 family member A1. | 0.962 |
| ABAT | HIBADH | ENSPPYP00000008008 | ENSPPYP00000019832 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 3-hydroxyisobutyrate dehydrogenase, mitochondrial; Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily. | 0.960 |
| ACSF3 | ALDH1B1 | ENSPPYP00000008636 | ENSPPYP00000021352 | Acyl-CoA synthetase family member 3. | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | 0.932 |
| ACSF3 | ALDH2 | ENSPPYP00000008636 | ENSPPYP00000005665 | Acyl-CoA synthetase family member 3. | Aldehyde dehydrogenase, mitochondrial; Is capable of converting retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family. | 0.932 |
| ACSS1 | ABAT | ENSPPYP00000012045 | ENSPPYP00000008008 | Acetyl-coenzyme A synthetase. | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.863 |
| ACSS1 | ACSS2 | ENSPPYP00000012045 | ENSPPYP00000012219 | Acetyl-coenzyme A synthetase. | ACSS2 isoform 8. | 0.904 |
| ACSS1 | AGXT2 | ENSPPYP00000012045 | ENSPPYP00000017192 | Acetyl-coenzyme A synthetase. | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.821 |
| ACSS1 | ALDH1B1 | ENSPPYP00000012045 | ENSPPYP00000021352 | Acetyl-coenzyme A synthetase. | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | 0.933 |
| ACSS1 | ALDH2 | ENSPPYP00000012045 | ENSPPYP00000005665 | Acetyl-coenzyme A synthetase. | Aldehyde dehydrogenase, mitochondrial; Is capable of converting retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family. | 0.933 |
| ACSS1 | ALDH6A1 | ENSPPYP00000012045 | ENSPPYP00000006799 | Acetyl-coenzyme A synthetase. | Aldehyde dehydrogenase 6 family member A1. | 0.925 |
| ACSS1 | HIBADH | ENSPPYP00000012045 | ENSPPYP00000019832 | Acetyl-coenzyme A synthetase. | 3-hydroxyisobutyrate dehydrogenase, mitochondrial; Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily. | 0.835 |
| ACSS2 | ABAT | ENSPPYP00000012219 | ENSPPYP00000008008 | ACSS2 isoform 8. | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.848 |
| ACSS2 | ACSS1 | ENSPPYP00000012219 | ENSPPYP00000012045 | ACSS2 isoform 8. | Acetyl-coenzyme A synthetase. | 0.904 |
| ACSS2 | AGXT2 | ENSPPYP00000012219 | ENSPPYP00000017192 | ACSS2 isoform 8. | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.821 |
| ACSS2 | ALDH1B1 | ENSPPYP00000012219 | ENSPPYP00000021352 | ACSS2 isoform 8. | Aldehyde dehydrogenase X, mitochondrial; ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (By similarity). | 0.933 |
