NUDT2 protein (Pongo abelii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY9	ENPP1	ENSPPYP00000007976	ENSPPYP00000019048	ADCY9 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	ENPP1 isoform 1.	0.650
ADCY9	ENPP3	ENSPPYP00000007976	ENSPPYP00000019047	ADCY9 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...]	0.650
ADCY9	NME2	ENSPPYP00000007976	ENSPPYP00000005726	ADCY9 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Nucleoside diphosphate kinase B; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically. Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter. Does not bind to duplex NHE I [...]	0.650
ADCY9	NME3	ENSPPYP00000007976	ENSPPYP00000007881	ADCY9 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Nucleoside diphosphate kinase.	0.650
ADCY9	NME4	ENSPPYP00000007976	ENSPPYP00000007822	ADCY9 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Nucleoside diphosphate kinase.	0.650
ADCY9	NME6	ENSPPYP00000007976	ENSPPYP00000015557	ADCY9 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Nucleoside diphosphate kinase.	0.661
ADCY9	NUDT2	ENSPPYP00000007976	ENSPPYP00000021430	ADCY9 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Nudix hydrolase 2.	0.912
CTPS1	CTPS2	ENSPPYP00000001712	ENSPPYP00000022544	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.991
CTPS1	ENPP1	ENSPPYP00000001712	ENSPPYP00000019048	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	ENPP1 isoform 1.	0.913
CTPS1	ENPP3	ENSPPYP00000001712	ENSPPYP00000019047	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...]	0.913
CTPS1	ITPA	ENSPPYP00000001712	ENSPPYP00000012088	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.638
CTPS1	NME2	ENSPPYP00000001712	ENSPPYP00000005726	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nucleoside diphosphate kinase B; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically. Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III(1) region of the MYC gene promoter. Does not bind to duplex NHE I [...]	0.946
CTPS1	NME3	ENSPPYP00000001712	ENSPPYP00000007881	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nucleoside diphosphate kinase.	0.946
CTPS1	NME4	ENSPPYP00000001712	ENSPPYP00000007822	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nucleoside diphosphate kinase.	0.946
CTPS1	NME6	ENSPPYP00000001712	ENSPPYP00000015557	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nucleoside diphosphate kinase.	0.950
CTPS1	NUDT2	ENSPPYP00000001712	ENSPPYP00000021430	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nudix hydrolase 2.	0.935
CTPS2	CTPS1	ENSPPYP00000022544	ENSPPYP00000001712	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.991
CTPS2	ENPP1	ENSPPYP00000022544	ENSPPYP00000019048	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	ENPP1 isoform 1.	0.909
CTPS2	ENPP3	ENSPPYP00000022544	ENSPPYP00000019047	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic [...]	0.909
CTPS2	ITPA	ENSPPYP00000022544	ENSPPYP00000012088	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.638