Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RIC1RIC1 isoform 3. (1344 aa)    
Predicted Functional Partners:
RGP1
RGP1 homolog, RAB6A GEF complex partner 1.
    
 0.993
COG8
Conserved oligomeric Golgi complex subunit 8.
   
 0.912
RAB33B
Ras-related protein Rab-33B; Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking (By similarity). It is involved in autophagy, acting as a modulator of autophagosome formation (By similarity); Belongs to the small GTPase superfamily. Rab family.
    
 0.910
RAB6A
Ras-related protein Rab-6A; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Involved in COPI-independent retrograde transport from the Golgi to the ER (By similarity); Belongs to the small GTPase superfamily. Rab family.
   
 0.862
RAB6B
RAB6B, member RAS oncogene family.
   
 0.862
ARFRP1
ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver.
    
 0.801
RAB33A
RAB33A, member RAS oncogene family.
    
 0.767
RAB34
RAB34 isoform 8.
   
 0.751
RAB36
RAB36, member RAS oncogene family.
   
 0.751
ARL1
ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.
    
  0.741
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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