STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK8DOCK8 isoform 2; Belongs to the DOCK family. (2024 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.970
LRCH1
LRCH1 isoform 2.
   
 
 0.921
LRCH3
LRCH3 isoform 8.
   
 
 0.921
CR201_G0040309
LRCH4 isoform 3.
   
 
 0.865
DOCK7
DOCK7 isoform 6; Belongs to the DOCK family.
  
 
 
0.820
RHOJ
Ras homolog family member J.
   
 0.819
DOCK6
DOCK6 isoform 2; Belongs to the DOCK family.
  
 
 
0.813
RHOQ
RHOQ isoform 1.
   
 0.766
LRCH2
LRCH2 isoform 1.
   
 
 0.762
ARPC3
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
   0.748
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.