STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIP5K1BPIP5K1B isoform 2. (540 aa)    
Predicted Functional Partners:
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
   
 0.947
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
  
 
0.945
PI4KA
PI4KA isoform 1; Belongs to the PI3/PI4-kinase family.
   
 0.941
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
    
0.935
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.
    
0.934
ENSPPYP00000018135
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1.
  
 
0.934
INPP5E
INPP5E isoform 2.
     
 0.931
PIP4K2C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.
    
0.930
SACM1L
Phosphatidylinositide phosphatase SAC1; Phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 4-phosphate (PtdIns(4)P) (By similarity). Has low activity towards PtdIns(3,5)P2 (By similarity).
    
 0.928
PI4K2A
Phosphatidylinositol 4-kinase type 2 alpha.
     
 0.925
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.