| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CREB1 | PRKACB | ENSPPYP00000014658 | ENSPPYP00000001400 | CREB1 isoform 1. | PRKACB isoform 9; Belongs to the protein kinase superfamily. | 0.985 |
| CREB1 | PRKACG | ENSPPYP00000014658 | ENSPPYP00000021585 | CREB1 isoform 1. | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.991 |
| ENSPPYP00000020490 | PRKACB | ENSPPYP00000020490 | ENSPPYP00000001400 | annotation not available | PRKACB isoform 9; Belongs to the protein kinase superfamily. | 0.989 |
| ENSPPYP00000020490 | PRKACG | ENSPPYP00000020490 | ENSPPYP00000021585 | annotation not available | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.983 |
| ENSPPYP00000020490 | PRKAR1A | ENSPPYP00000020490 | ENSPPYP00000010056 | annotation not available | cAMP-dependent protein kinase type I-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. | 0.900 |
| ENSPPYP00000020490 | PRKAR2A | ENSPPYP00000020490 | ENSPPYP00000015541 | annotation not available | Protein kinase cAMP-dependent type II regulatory subunit alpha. | 0.970 |
| ENSPPYP00000020490 | PRKAR2B | ENSPPYP00000020490 | ENSPPYP00000020060 | annotation not available | PRKAR2B isoform 1. | 0.980 |
| PDE4D | PPP1R1B | ENSPPYP00000017305 | ENSPPYP00000009533 | Phosphodiesterase. | Protein phosphatase 1 regulatory inhibitor subunit 1B. | 0.544 |
| PDE4D | PRKACB | ENSPPYP00000017305 | ENSPPYP00000001400 | Phosphodiesterase. | PRKACB isoform 9; Belongs to the protein kinase superfamily. | 0.977 |
| PDE4D | PRKACG | ENSPPYP00000017305 | ENSPPYP00000021585 | Phosphodiesterase. | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.986 |
| PDE4D | PRKAR1A | ENSPPYP00000017305 | ENSPPYP00000010056 | Phosphodiesterase. | cAMP-dependent protein kinase type I-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. | 0.508 |
| PLN | PRKACB | ENSPPYP00000020960 | ENSPPYP00000001400 | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | PRKACB isoform 9; Belongs to the protein kinase superfamily. | 0.984 |
| PLN | PRKACG | ENSPPYP00000020960 | ENSPPYP00000021585 | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.984 |
| PPP1R1B | PDE4D | ENSPPYP00000009533 | ENSPPYP00000017305 | Protein phosphatase 1 regulatory inhibitor subunit 1B. | Phosphodiesterase. | 0.544 |
| PPP1R1B | PRKACB | ENSPPYP00000009533 | ENSPPYP00000001400 | Protein phosphatase 1 regulatory inhibitor subunit 1B. | PRKACB isoform 9; Belongs to the protein kinase superfamily. | 0.988 |
| PPP1R1B | PRKACG | ENSPPYP00000009533 | ENSPPYP00000021585 | Protein phosphatase 1 regulatory inhibitor subunit 1B. | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.988 |
| PRKACB | CREB1 | ENSPPYP00000001400 | ENSPPYP00000014658 | PRKACB isoform 9; Belongs to the protein kinase superfamily. | CREB1 isoform 1. | 0.985 |
| PRKACB | ENSPPYP00000020490 | ENSPPYP00000001400 | ENSPPYP00000020490 | PRKACB isoform 9; Belongs to the protein kinase superfamily. | annotation not available | 0.989 |
| PRKACB | PDE4D | ENSPPYP00000001400 | ENSPPYP00000017305 | PRKACB isoform 9; Belongs to the protein kinase superfamily. | Phosphodiesterase. | 0.977 |
| PRKACB | PLN | ENSPPYP00000001400 | ENSPPYP00000020960 | PRKACB isoform 9; Belongs to the protein kinase superfamily. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.984 |
