STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TJP2TJP2 isoform 3; Belongs to the MAGUK family. (1186 aa)    
Predicted Functional Partners:
F11R
F11R isoform 1.
   
 0.961
RAPGEF2
RAPGEF2 isoform 1.
    
 0.923
GJA1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
 0.752
YAP1
YAP1 isoform 2.
   
 0.724
WWTR1
WW domain containing transcription regulator 1.
   
 0.680
TJP1
TJP1 isoform 1; Belongs to the MAGUK family.
    
 
0.652
CASP3
CASP3 isoform 1; Belongs to the peptidase C14A family.
     
 0.610
OCLN
Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
   
 
 0.604
CGN
CGN isoform 4.
   
 0.597
GJA4
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
 0.591
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.