STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GNAQG protein subunit alpha q. (359 aa)    
Predicted Functional Partners:
PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.998
HRH1
Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family.
    
 0.998
TBXA2R
Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.995
CCKBR
CCKBR isoform 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.994
CCKAR
Cholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.993
GNB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.990
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.990
AGTR1
Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.988
LPAR1
Lysophosphatidic acid receptor 1.
    
 0.987
S1PR2
Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.982
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.