STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLE4TLE4 isoform 4. (743 aa)    
Predicted Functional Partners:
TLE1
TLE1 isoform 1.
  
 
0.930
CR201_G0044248
AES isoform 2.
    
0.902
TLE3
TLE family member 3, transcriptional corepressor.
  
 
0.873
RASEF
RASEF isoform 2.
    
 
 0.843
FRMD3
FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.
      
 0.843
PSAT1
Phosphoserine aminotransferase.
      
 0.840
TLE2
TLE2 isoform 1.
  
 
 
0.822
CR201_G0012836
TCF7L2 isoform 2.
    
 0.779
RIPPLY1
RIPPLY1 isoform 2.
    
 
 0.764
RIPPLY2
Ripply transcriptional repressor 2.
    
 
 0.755
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.