STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRMD3FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. (556 aa)    
Predicted Functional Partners:
RASEF
RASEF isoform 2.
      
 0.882
TLE1
TLE1 isoform 1.
      
 0.865
PSAT1
Phosphoserine aminotransferase.
      
 0.863
TLE4
TLE4 isoform 4.
      
 0.843
GNAQ
G protein subunit alpha q.
      
 0.809
SNRPN
Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events; Belongs to the snRNP SmB/SmN family.
    
 
 0.787
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 
 0.724
CASK
CASK isoform 2; Belongs to the MAGUK family.
   
 0.649
GNA14
G protein subunit alpha 14.
      
 0.560
ATP5MG
ATP synthase subunit g, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...]
      
 0.525
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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