| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADRM1 | PSMD14 | ENSPPYP00000012517 | ENSPPYP00000014374 | Adhesion regulating molecule 1. | Proteasome 26S subunit, non-ATPase 14. | 0.977 |
| ADRM1 | PSMD4 | ENSPPYP00000012517 | ENSPPYP00000024378 | Adhesion regulating molecule 1. | PSMD4 isoform 1. | 0.995 |
| ADRM1 | UBC | ENSPPYP00000012517 | ENSPPYP00000005811 | Adhesion regulating molecule 1. | UBC isoform 2. | 0.946 |
| ADRM1 | UBQLN1 | ENSPPYP00000012517 | ENSPPYP00000021651 | Adhesion regulating molecule 1. | Ubiquilin-1; Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin- proteasome system (UPS), autophagy and endoplasmic reticulum-associated protein degradation (ERAD) pathway. Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. Plays a role in the ERAD pathway via its interaction with ER-localized proteins UBXN4, VCP and HERPUD1 and may form a lin [...] | 0.908 |
| ADRM1 | UBQLN2 | ENSPPYP00000012517 | ENSPPYP00000022835 | Adhesion regulating molecule 1. | UBQLN2 isoform 1. | 0.956 |
| ADRM1 | UBQLN4 | ENSPPYP00000012517 | ENSPPYP00000000849 | Adhesion regulating molecule 1. | UBQLN4 isoform 1. | 0.706 |
| DESI1 | PSMD4 | ENSPPYP00000023767 | ENSPPYP00000024378 | DESI1 isoform 1. | PSMD4 isoform 1. | 0.915 |
| DESI1 | UBQLN1 | ENSPPYP00000023767 | ENSPPYP00000021651 | DESI1 isoform 1. | Ubiquilin-1; Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin- proteasome system (UPS), autophagy and endoplasmic reticulum-associated protein degradation (ERAD) pathway. Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. Plays a role in the ERAD pathway via its interaction with ER-localized proteins UBXN4, VCP and HERPUD1 and may form a lin [...] | 0.926 |
| DESI1 | UBQLN2 | ENSPPYP00000023767 | ENSPPYP00000022835 | DESI1 isoform 1. | UBQLN2 isoform 1. | 0.926 |
| DESI1 | UBQLN4 | ENSPPYP00000023767 | ENSPPYP00000000849 | DESI1 isoform 1. | UBQLN4 isoform 1. | 0.932 |
| EPS15 | UBC | ENSPPYP00000001582 | ENSPPYP00000005811 | Epidermal growth factor receptor pathway substrate 15. | UBC isoform 2. | 0.952 |
| EPS15 | UBQLN1 | ENSPPYP00000001582 | ENSPPYP00000021651 | Epidermal growth factor receptor pathway substrate 15. | Ubiquilin-1; Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin- proteasome system (UPS), autophagy and endoplasmic reticulum-associated protein degradation (ERAD) pathway. Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. Plays a role in the ERAD pathway via its interaction with ER-localized proteins UBXN4, VCP and HERPUD1 and may form a lin [...] | 0.845 |
| EPS15 | UBQLN2 | ENSPPYP00000001582 | ENSPPYP00000022835 | Epidermal growth factor receptor pathway substrate 15. | UBQLN2 isoform 1. | 0.628 |
| EPS15 | UBQLN4 | ENSPPYP00000001582 | ENSPPYP00000000849 | Epidermal growth factor receptor pathway substrate 15. | UBQLN4 isoform 1. | 0.654 |
| PSEN1 | UBC | ENSPPYP00000006781 | ENSPPYP00000005811 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] | UBC isoform 2. | 0.531 |
| PSEN1 | UBQLN1 | ENSPPYP00000006781 | ENSPPYP00000021651 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] | Ubiquilin-1; Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin- proteasome system (UPS), autophagy and endoplasmic reticulum-associated protein degradation (ERAD) pathway. Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. Plays a role in the ERAD pathway via its interaction with ER-localized proteins UBXN4, VCP and HERPUD1 and may form a lin [...] | 0.830 |
| PSEN1 | UBQLN2 | ENSPPYP00000006781 | ENSPPYP00000022835 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] | UBQLN2 isoform 1. | 0.498 |
| PSEN1 | UBQLN4 | ENSPPYP00000006781 | ENSPPYP00000000849 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] | UBQLN4 isoform 1. | 0.451 |
| PSMD14 | ADRM1 | ENSPPYP00000014374 | ENSPPYP00000012517 | Proteasome 26S subunit, non-ATPase 14. | Adhesion regulating molecule 1. | 0.977 |
| PSMD14 | PSMD4 | ENSPPYP00000014374 | ENSPPYP00000024378 | Proteasome 26S subunit, non-ATPase 14. | PSMD4 isoform 1. | 0.999 |
