STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSD17B3Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa)    
Predicted Functional Partners:
HSD17B2
Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.984
CYP17A1
CYP17A1 isoform 1; Belongs to the cytochrome P450 family.
   
 0.971
HSD3B1
HSD3B1 isoform 1; Belongs to the 3-beta-HSD family.
  
 0.963
SRD5A2
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).
   
 
 0.959
SRD5A1
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).
   
 
 0.958
CYP19A1
Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.955
HSD17B8
HSD17B8 isoform 1.
 
 0.951
CYP11B2
Cytochrome P450 11B2, mitochondrial isoform X1.
   
 0.945
HSD17B6
Hydroxysteroid 17-beta dehydrogenase 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
0.935
SRD5A3
Steroid 5 alpha-reductase 3.
     
 0.935
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.