STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDRD7Tudor domain-containing protein 7; Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis (By similarity). (1098 aa)    
Predicted Functional Partners:
PIWIL3
Piwi like RNA-mediated gene silencing 3; Belongs to the argonaute family.
   
 0.810
CDK17
Cyclin dependent kinase 17.
   
 
 0.753
GABPB1
GABPB1 isoform 1.
    
 0.752
PIWIL1
Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.
   
 0.734
PIWIL2
Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.
   
 0.728
CCDC180
CCDC180 isoform 2.
      
 0.686
CABLES1
CABLES1 isoform 1.
      
 0.684
CDK18
Cyclin-dependent kinase 18; May play a role in signal transduction cascades in terminally differentiated cells.
   
 
 0.627
PIWIL4
PIWIL4 isoform 3; Belongs to the argonaute family.
   
 0.620
CR201_G0039079
TDRD9 isoform 3.
   
 0.585
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.