| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASK | EPS8 | ENSPPYP00000022673 | ENSPPYP00000004948 | CASK isoform 2; Belongs to the MAGUK family. | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | 0.828 |
| CASK | MPP1 | ENSPPYP00000022673 | ENSPPYP00000023388 | CASK isoform 2; Belongs to the MAGUK family. | 55 kDa erythrocyte membrane protein; Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity). Belongs to the MAGUK family. | 0.701 |
| CASK | MYO15A | ENSPPYP00000022673 | ENSPPYP00000009048 | CASK isoform 2; Belongs to the MAGUK family. | MYO15A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.651 |
| CASK | MYO15B | ENSPPYP00000022673 | ENSPPYP00000009693 | CASK isoform 2; Belongs to the MAGUK family. | MYO15B isoform 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.515 |
| CASK | MYO3A | ENSPPYP00000022673 | ENSPPYP00000002509 | CASK isoform 2; Belongs to the MAGUK family. | MYO3A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.665 |
| CASK | WHRN | ENSPPYP00000022673 | ENSPPYP00000021890 | CASK isoform 2; Belongs to the MAGUK family. | WHRN isoform 2. | 0.922 |
| CR201_G0023224 | EPS8 | ENSPPYP00000004234 | ENSPPYP00000004948 | MYO7A isoform 2. | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | 0.577 |
| CR201_G0023224 | RPGRIP1L | ENSPPYP00000004234 | ENSPPYP00000008303 | MYO7A isoform 2. | RPGRIP1L isoform 3. | 0.751 |
| CR201_G0023224 | TTC21B | ENSPPYP00000004234 | ENSPPYP00000014395 | MYO7A isoform 2. | TTC21B isoform 1. | 0.631 |
| CR201_G0023224 | WHRN | ENSPPYP00000004234 | ENSPPYP00000021890 | MYO7A isoform 2. | WHRN isoform 2. | 0.846 |
| EPS8 | CASK | ENSPPYP00000004948 | ENSPPYP00000022673 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | CASK isoform 2; Belongs to the MAGUK family. | 0.828 |
| EPS8 | CR201_G0023224 | ENSPPYP00000004948 | ENSPPYP00000004234 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | MYO7A isoform 2. | 0.577 |
| EPS8 | MPP1 | ENSPPYP00000004948 | ENSPPYP00000023388 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | 55 kDa erythrocyte membrane protein; Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity). Belongs to the MAGUK family. | 0.795 |
| EPS8 | MYO15A | ENSPPYP00000004948 | ENSPPYP00000009048 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | MYO15A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.849 |
| EPS8 | MYO15B | ENSPPYP00000004948 | ENSPPYP00000009693 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | MYO15B isoform 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.789 |
| EPS8 | MYO3A | ENSPPYP00000004948 | ENSPPYP00000002509 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | MYO3A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.861 |
| EPS8 | WHRN | ENSPPYP00000004948 | ENSPPYP00000021890 | Epidermal growth factor receptor kinase substrate 8; Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and acti [...] | WHRN isoform 2. | 0.897 |
| IFT88 | RPGRIP1L | ENSPPYP00000005916 | ENSPPYP00000008303 | IFT88 isoform 2. | RPGRIP1L isoform 3. | 0.749 |
| IFT88 | TTC21B | ENSPPYP00000005916 | ENSPPYP00000014395 | IFT88 isoform 2. | TTC21B isoform 1. | 0.899 |
| IFT88 | WHRN | ENSPPYP00000005916 | ENSPPYP00000021890 | IFT88 isoform 2. | WHRN isoform 2. | 0.828 |
