ASS1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ASS1

ASS1 isoform 1. (359 aa)

Predicted Functional Partners:

ASL

0.995

OTC

0.993

CPS1

0.983

CAD

0.973

NOS2

0.940

ADSS2

0.929

ADSS1

0.929

NOS3

0.928

NOS1

0.927

GOT1L1

0.924

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADSS1	ADSS2	ENSPPYP00000007034	ENSPPYP00000000054	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.901
ADSS1	ASL	ENSPPYP00000007034	ENSPPYP00000019643	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Argininosuccinate lyase isoform X1.	0.579
ADSS1	ASS1	ENSPPYP00000007034	ENSPPYP00000022070	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	ASS1 isoform 1.	0.929
ADSS1	CAD	ENSPPYP00000007034	ENSPPYP00000014025	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.945
ADSS1	CPS1	ENSPPYP00000007034	ENSPPYP00000014680	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Carbamoyl-phosphate synthase 1.	0.477
ADSS1	GOT1L1	ENSPPYP00000007034	ENSPPYP00000020754	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Glutamic-oxaloacetic transaminase 1 like 1.	0.923
ADSS2	ADSS1	ENSPPYP00000000054	ENSPPYP00000007034	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.901
ADSS2	ASL	ENSPPYP00000000054	ENSPPYP00000019643	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Argininosuccinate lyase isoform X1.	0.579
ADSS2	ASS1	ENSPPYP00000000054	ENSPPYP00000022070	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	ASS1 isoform 1.	0.929
ADSS2	CAD	ENSPPYP00000000054	ENSPPYP00000014025	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.945
ADSS2	CPS1	ENSPPYP00000000054	ENSPPYP00000014680	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Carbamoyl-phosphate synthase 1.	0.477
ADSS2	GOT1L1	ENSPPYP00000000054	ENSPPYP00000020754	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Glutamic-oxaloacetic transaminase 1 like 1.	0.923
ASL	ADSS1	ENSPPYP00000019643	ENSPPYP00000007034	Argininosuccinate lyase isoform X1.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.579
ASL	ADSS2	ENSPPYP00000019643	ENSPPYP00000000054	Argininosuccinate lyase isoform X1.	Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.579
ASL	ASS1	ENSPPYP00000019643	ENSPPYP00000022070	Argininosuccinate lyase isoform X1.	ASS1 isoform 1.	0.995
ASL	CAD	ENSPPYP00000019643	ENSPPYP00000014025	Argininosuccinate lyase isoform X1.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.728
ASL	CPS1	ENSPPYP00000019643	ENSPPYP00000014680	Argininosuccinate lyase isoform X1.	Carbamoyl-phosphate synthase 1.	0.730
ASL	NOS1	ENSPPYP00000019643	ENSPPYP00000005707	Argininosuccinate lyase isoform X1.	NOS1 isoform 2.	0.939
ASL	NOS2	ENSPPYP00000019643	ENSPPYP00000009087	Argininosuccinate lyase isoform X1.	Nitric oxide synthase; Produces nitric oxide (NO).	0.939
ASL	NOS3	ENSPPYP00000019643	ENSPPYP00000020384	Argininosuccinate lyase isoform X1.	NOS3 isoform 2.	0.939