| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKT1 | AKT2 | ENSPPYP00000007036 | ENSPPYP00000011178 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.999 |
| AKT1 | AKT3 | ENSPPYP00000007036 | ENSPPYP00000000057 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.991 |
| AKT1 | PRKAA1 | ENSPPYP00000007036 | ENSPPYP00000017227 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 5'-AMP-activated protein kinase catalytic subunit alpha-1; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] | 0.550 |
| AKT1 | PRKAA2 | ENSPPYP00000007036 | ENSPPYP00000001519 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 5'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] | 0.485 |
| AKT1 | RHEB | ENSPPYP00000007036 | ENSPPYP00000020403 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | RHEB isoform 1. | 0.627 |
| AKT1 | TBC1D7 | ENSPPYP00000007036 | ENSPPYP00000018162 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | TBC1 domain family member 7. | 0.935 |
| AKT1 | TSC1 | ENSPPYP00000007036 | ENSPPYP00000022110 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | TSC1 isoform 8. | 0.984 |
| AKT1 | TSC2 | ENSPPYP00000007036 | ENSPPYP00000007907 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | TSC2 isoform 1. | 0.989 |
| AKT2 | AKT1 | ENSPPYP00000011178 | ENSPPYP00000007036 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.999 |
| AKT2 | AKT3 | ENSPPYP00000011178 | ENSPPYP00000000057 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.984 |
| AKT2 | PRKAA1 | ENSPPYP00000011178 | ENSPPYP00000017227 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 5'-AMP-activated protein kinase catalytic subunit alpha-1; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] | 0.527 |
| AKT2 | PRKAA2 | ENSPPYP00000011178 | ENSPPYP00000001519 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 5'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] | 0.505 |
| AKT2 | TBC1D7 | ENSPPYP00000011178 | ENSPPYP00000018162 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | TBC1 domain family member 7. | 0.930 |
| AKT2 | TSC1 | ENSPPYP00000011178 | ENSPPYP00000022110 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | TSC1 isoform 8. | 0.985 |
| AKT2 | TSC2 | ENSPPYP00000011178 | ENSPPYP00000007907 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | TSC2 isoform 1. | 0.987 |
| AKT3 | AKT1 | ENSPPYP00000000057 | ENSPPYP00000007036 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.991 |
| AKT3 | AKT2 | ENSPPYP00000000057 | ENSPPYP00000011178 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.984 |
| AKT3 | PRKAA1 | ENSPPYP00000000057 | ENSPPYP00000017227 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 5'-AMP-activated protein kinase catalytic subunit alpha-1; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] | 0.495 |
| AKT3 | PRKAA2 | ENSPPYP00000000057 | ENSPPYP00000001519 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 5'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] | 0.499 |
| AKT3 | TBC1D7 | ENSPPYP00000000057 | ENSPPYP00000018162 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | TBC1 domain family member 7. | 0.982 |
