ARSD protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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Assay-based Predictions

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARSD	ARSK	ENSPPYP00000022473	ENSPPYP00000017485	ARSD isoform 1.	ARSK isoform 1.	0.646
ARSD	CER1	ENSPPYP00000022473	ENSPPYP00000021520	ARSD isoform 1.	CER1 isoform 1.	0.807
ARSD	CTPS2	ENSPPYP00000022473	ENSPPYP00000022544	ARSD isoform 1.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.766
ARSD	DDX3X	ENSPPYP00000022473	ENSPPYP00000022671	ARSD isoform 1.	ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.	0.594
ARSD	EIF2S3	ENSPPYP00000022473	ENSPPYP00000022595	ARSD isoform 1.	Eukaryotic translation initiation factor 2 subunit 3; As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In o [...]	0.562
ARSD	KDM6A	ENSPPYP00000022473	ENSPPYP00000022687	ARSD isoform 1.	UTY isoform 5.	0.566
ARSD	MED14	ENSPPYP00000022473	ENSPPYP00000022666	ARSD isoform 1.	Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.855
ARSD	PNPLA4	ENSPPYP00000022473	ENSPPYP00000022491	ARSD isoform 1.	PNPLA4 isoform 1.	0.763
ARSD	SUMF1	ENSPPYP00000022473	ENSPPYP00000015319	ARSD isoform 1.	Sulfatase modifying factor 1.	0.658
ARSD	SUMF2	ENSPPYP00000022473	ENSPPYP00000019664	ARSD isoform 1.	Inactive C-alpha-formylglycine-generating enzyme 2; Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1. Belongs to the sulfatase-modifying factor family.	0.562
ARSK	ARSD	ENSPPYP00000017485	ENSPPYP00000022473	ARSK isoform 1.	ARSD isoform 1.	0.646
ARSK	SUMF1	ENSPPYP00000017485	ENSPPYP00000015319	ARSK isoform 1.	Sulfatase modifying factor 1.	0.734
ARSK	SUMF2	ENSPPYP00000017485	ENSPPYP00000019664	ARSK isoform 1.	Inactive C-alpha-formylglycine-generating enzyme 2; Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1. Belongs to the sulfatase-modifying factor family.	0.788
CER1	ARSD	ENSPPYP00000021520	ENSPPYP00000022473	CER1 isoform 1.	ARSD isoform 1.	0.807
CTPS2	ARSD	ENSPPYP00000022544	ENSPPYP00000022473	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	ARSD isoform 1.	0.766
CTPS2	DDX3X	ENSPPYP00000022544	ENSPPYP00000022671	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.	0.727
CTPS2	EIF2S3	ENSPPYP00000022544	ENSPPYP00000022595	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Eukaryotic translation initiation factor 2 subunit 3; As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In o [...]	0.765
CTPS2	KDM6A	ENSPPYP00000022544	ENSPPYP00000022687	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	UTY isoform 5.	0.758
CTPS2	MED14	ENSPPYP00000022544	ENSPPYP00000022666	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.878
CTPS2	PNPLA4	ENSPPYP00000022544	ENSPPYP00000022491	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	PNPLA4 isoform 1.	0.831