| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC22 | CCDC93 | ENSPPYP00000022770 | ENSPPYP00000014278 | CCDC22 isoform 1. | Coiled-coil domain containing 93. | 0.974 |
| CCDC22 | COMMD10 | ENSPPYP00000022770 | ENSPPYP00000017563 | CCDC22 isoform 1. | COMM domain containing 10. | 0.978 |
| CCDC22 | COMMD2 | ENSPPYP00000022770 | ENSPPYP00000015880 | CCDC22 isoform 1. | COMM domain-containing protein 2; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. | 0.983 |
| CCDC22 | COMMD5 | ENSPPYP00000022770 | ENSPPYP00000021301 | CCDC22 isoform 1. | COMM domain containing 5. | 0.982 |
| CCDC22 | COMMD8 | ENSPPYP00000022770 | ENSPPYP00000016432 | CCDC22 isoform 1. | COMM domain containing 8. | 0.983 |
| CCDC22 | COMMD9 | ENSPPYP00000022770 | ENSPPYP00000003848 | CCDC22 isoform 1. | COMM domain containing 9. | 0.983 |
| CCDC22 | CR201_G0003257 | ENSPPYP00000022770 | ENSPPYP00000013806 | CCDC22 isoform 1. | COMMD1 isoform 4. | 0.983 |
| CCDC22 | CR201_G0007515 | ENSPPYP00000022770 | ENSPPYP00000006172 | CCDC22 isoform 1. | COMMD6 isoform 1. | 0.981 |
| CCDC22 | VPS26C | ENSPPYP00000022770 | ENSPPYP00000012737 | CCDC22 isoform 1. | Vacuolar protein sorting-associated protein 26C; Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retriever and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of nu [...] | 0.969 |
| CCDC22 | VPS35L | ENSPPYP00000022770 | ENSPPYP00000008083 | CCDC22 isoform 1. | VPS35 endosomal protein sorting factor-like; Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numero [...] | 0.976 |
| CCDC93 | CCDC22 | ENSPPYP00000014278 | ENSPPYP00000022770 | Coiled-coil domain containing 93. | CCDC22 isoform 1. | 0.974 |
| CCDC93 | COMMD10 | ENSPPYP00000014278 | ENSPPYP00000017563 | Coiled-coil domain containing 93. | COMM domain containing 10. | 0.955 |
| CCDC93 | COMMD2 | ENSPPYP00000014278 | ENSPPYP00000015880 | Coiled-coil domain containing 93. | COMM domain-containing protein 2; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. | 0.966 |
| CCDC93 | COMMD5 | ENSPPYP00000014278 | ENSPPYP00000021301 | Coiled-coil domain containing 93. | COMM domain containing 5. | 0.966 |
| CCDC93 | COMMD8 | ENSPPYP00000014278 | ENSPPYP00000016432 | Coiled-coil domain containing 93. | COMM domain containing 8. | 0.966 |
| CCDC93 | COMMD9 | ENSPPYP00000014278 | ENSPPYP00000003848 | Coiled-coil domain containing 93. | COMM domain containing 9. | 0.963 |
| CCDC93 | CR201_G0003257 | ENSPPYP00000014278 | ENSPPYP00000013806 | Coiled-coil domain containing 93. | COMMD1 isoform 4. | 0.967 |
| CCDC93 | CR201_G0007515 | ENSPPYP00000014278 | ENSPPYP00000006172 | Coiled-coil domain containing 93. | COMMD6 isoform 1. | 0.964 |
| CCDC93 | VPS26C | ENSPPYP00000014278 | ENSPPYP00000012737 | Coiled-coil domain containing 93. | Vacuolar protein sorting-associated protein 26C; Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retriever and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of nu [...] | 0.967 |
| CCDC93 | VPS35L | ENSPPYP00000014278 | ENSPPYP00000008083 | Coiled-coil domain containing 93. | VPS35 endosomal protein sorting factor-like; Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numero [...] | 0.969 |
