| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FOXP2 | FOXP3 | ENSPPYP00000020095 | ENSPPYP00000022771 | FOXP2 isoform 11. | FOXP3 isoform 1. | 0.920 |
| FOXP2 | IFNG | ENSPPYP00000020095 | ENSPPYP00000005405 | FOXP2 isoform 11. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.434 |
| FOXP2 | IL2RA | ENSPPYP00000020095 | ENSPPYP00000002390 | FOXP2 isoform 11. | Interleukin 2 receptor subunit alpha. | 0.423 |
| FOXP2 | NFATC2 | ENSPPYP00000020095 | ENSPPYP00000012442 | FOXP2 isoform 11. | Nuclear factor of activated T cells 2. | 0.766 |
| FOXP2 | RUNX1 | ENSPPYP00000020095 | ENSPPYP00000012719 | FOXP2 isoform 11. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.677 |
| FOXP3 | FOXP2 | ENSPPYP00000022771 | ENSPPYP00000020095 | FOXP3 isoform 1. | FOXP2 isoform 11. | 0.920 |
| FOXP3 | GATA3 | ENSPPYP00000022771 | ENSPPYP00000002408 | FOXP3 isoform 1. | GATA binding protein 3. | 0.840 |
| FOXP3 | IFNG | ENSPPYP00000022771 | ENSPPYP00000005405 | FOXP3 isoform 1. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.830 |
| FOXP3 | IL2 | ENSPPYP00000022771 | ENSPPYP00000016803 | FOXP3 isoform 1. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | 0.953 |
| FOXP3 | IL2RA | ENSPPYP00000022771 | ENSPPYP00000002390 | FOXP3 isoform 1. | Interleukin 2 receptor subunit alpha. | 0.933 |
| FOXP3 | NFATC2 | ENSPPYP00000022771 | ENSPPYP00000012442 | FOXP3 isoform 1. | Nuclear factor of activated T cells 2. | 0.864 |
| FOXP3 | RORC | ENSPPYP00000022771 | ENSPPYP00000000995 | FOXP3 isoform 1. | Nuclear receptor ROR-gamma; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respective [...] | 0.961 |
| FOXP3 | RUNX1 | ENSPPYP00000022771 | ENSPPYP00000012719 | FOXP3 isoform 1. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.973 |
| FOXP3 | SMAD3 | ENSPPYP00000022771 | ENSPPYP00000007465 | FOXP3 isoform 1. | Mothers against decapentaplegic homolog. | 0.903 |
| FOXP3 | STAT3 | ENSPPYP00000022771 | ENSPPYP00000009437 | FOXP3 isoform 1. | Signal transducer and activator of transcription. | 0.910 |
| GATA3 | FOXP3 | ENSPPYP00000002408 | ENSPPYP00000022771 | GATA binding protein 3. | FOXP3 isoform 1. | 0.840 |
| GATA3 | IFNG | ENSPPYP00000002408 | ENSPPYP00000005405 | GATA binding protein 3. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.658 |
| GATA3 | IL2 | ENSPPYP00000002408 | ENSPPYP00000016803 | GATA binding protein 3. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. | 0.471 |
| GATA3 | IL2RA | ENSPPYP00000002408 | ENSPPYP00000002390 | GATA binding protein 3. | Interleukin 2 receptor subunit alpha. | 0.510 |
| GATA3 | RORC | ENSPPYP00000002408 | ENSPPYP00000000995 | GATA binding protein 3. | Nuclear receptor ROR-gamma; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respective [...] | 0.530 |
