STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HUWE1HUWE1 isoform 1. (4373 aa)    
Predicted Functional Partners:
MCL1
MCL1 apoptosis regulator, BCL2 family member.
    
 
 0.960
UBC
UBC isoform 2.
   
 0.934
DDIT4
DNA damage inducible transcript 4.
    
 
 0.895
HSD17B10
Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.874
MYC
MYC isoform 1.
    
 
 0.824
UBA52
UBA52 isoform 10.
    
 0.798
PHAX
Phosphorylated adaptor for RNA export.
    
 
 0.755
TRIP12
TRIP12 isoform 4.
   
 
0.739
ZBTB17
Zinc finger and BTB domain containing 17.
    
 
 0.733
UBR4
UBR4 isoform 1.
   
 
 0.720
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.