MED12 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNC	CDK8	ENSPPYP00000018878	ENSPPYP00000005956	CCNC isoform 1; Belongs to the cyclin family.	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	0.997
CCNC	MED1	ENSPPYP00000018878	ENSPPYP00000009539	CCNC isoform 1; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	0.994
CCNC	MED12	ENSPPYP00000018878	ENSPPYP00000022889	CCNC isoform 1; Belongs to the cyclin family.	MED12 isoform 3.	0.994
CCNC	MED13	ENSPPYP00000018878	ENSPPYP00000009885	CCNC isoform 1; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.991
CCNC	MED13L	ENSPPYP00000018878	ENSPPYP00000005698	CCNC isoform 1; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.988
CCNC	MED14	ENSPPYP00000018878	ENSPPYP00000022666	CCNC isoform 1; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.995
CCNC	MED19	ENSPPYP00000018878	ENSPPYP00000003751	CCNC isoform 1; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.986
CCNC	MED20	ENSPPYP00000018878	ENSPPYP00000018572	CCNC isoform 1; Belongs to the cyclin family.	Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.992
CCNC	MED23	ENSPPYP00000018878	ENSPPYP00000024779	CCNC isoform 1; Belongs to the cyclin family.	Mediator complex subunit 23.	0.994
CCNC	MED30	ENSPPYP00000018878	ENSPPYP00000021132	CCNC isoform 1; Belongs to the cyclin family.	Mediator complex subunit 30.	0.982
CDK8	CCNC	ENSPPYP00000005956	ENSPPYP00000018878	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	CCNC isoform 1; Belongs to the cyclin family.	0.997
CDK8	MED1	ENSPPYP00000005956	ENSPPYP00000009539	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Acts as a coactivator for [...]	0.988
CDK8	MED12	ENSPPYP00000005956	ENSPPYP00000022889	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	MED12 isoform 3.	0.993
CDK8	MED13	ENSPPYP00000005956	ENSPPYP00000009885	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.982
CDK8	MED13L	ENSPPYP00000005956	ENSPPYP00000005698	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.987
CDK8	MED14	ENSPPYP00000005956	ENSPPYP00000022666	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.990
CDK8	MED19	ENSPPYP00000005956	ENSPPYP00000003751	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.984
CDK8	MED20	ENSPPYP00000005956	ENSPPYP00000018572	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.983
CDK8	MED23	ENSPPYP00000005956	ENSPPYP00000024779	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Mediator complex subunit 23.	0.986
CDK8	MED30	ENSPPYP00000005956	ENSPPYP00000021132	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Mediator complex subunit 30.	0.989