STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAP1L2Nucleosome assembly protein 1 like 2; Belongs to the nucleosome assembly protein (NAP) family. (460 aa)    
Predicted Functional Partners:
CDX4
CDX4 isoform 1.
      
 0.678
NAP1L3
Nucleosome assembly protein 1-like 3.
  
 
0.620
H2AZ1
Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...]
   
 
 0.589
H2AZ2
Histone H2A; Belongs to the histone H2A family.
   
 
 0.589
MAGEB2
MAGE family member B2.
   
 
 0.585
PPP1R1A
PPP1R1A isoform 1.
      
 0.569
SHISA4
Shisa family member 4.
   
 
 0.546
IPO9
IPO9 isoform 1.
   
 
 0.546
UBE2O
Ubiquitin conjugating enzyme E2 O.
    
 
 0.524
SDAD1
Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.
    
 
 0.492
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.