| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATF4 | MAPK3 | ENSPPYP00000013213 | ENSPPYP00000008184 | ATF4 isoform 1. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.915 |
| ATF4 | RPS6KA1 | ENSPPYP00000013213 | ENSPPYP00000001941 | ATF4 isoform 1. | Ribosomal protein S6 kinase. | 0.930 |
| ATF4 | RPS6KA6 | ENSPPYP00000013213 | ENSPPYP00000022960 | ATF4 isoform 1. | Ribosomal protein S6 kinase. | 0.930 |
| ESR1 | ESR2 | ENSPPYP00000019159 | ENSPPYP00000006703 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | ESR2 isoform 12. | 0.999 |
| ESR1 | MAPK3 | ENSPPYP00000019159 | ENSPPYP00000008184 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.977 |
| ESR1 | RPS6KA1 | ENSPPYP00000019159 | ENSPPYP00000001941 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Ribosomal protein S6 kinase. | 0.924 |
| ESR1 | RPS6KA6 | ENSPPYP00000019159 | ENSPPYP00000022960 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Ribosomal protein S6 kinase. | 0.910 |
| ESR1 | TSC2 | ENSPPYP00000019159 | ENSPPYP00000007907 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | TSC2 isoform 1. | 0.649 |
| ESR2 | ESR1 | ENSPPYP00000006703 | ENSPPYP00000019159 | ESR2 isoform 12. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.999 |
| ESR2 | MAPK3 | ENSPPYP00000006703 | ENSPPYP00000008184 | ESR2 isoform 12. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.958 |
| ESR2 | RPS6KA1 | ENSPPYP00000006703 | ENSPPYP00000001941 | ESR2 isoform 12. | Ribosomal protein S6 kinase. | 0.916 |
| ESR2 | RPS6KA6 | ENSPPYP00000006703 | ENSPPYP00000022960 | ESR2 isoform 12. | Ribosomal protein S6 kinase. | 0.910 |
| ESR2 | TSC2 | ENSPPYP00000006703 | ENSPPYP00000007907 | ESR2 isoform 12. | TSC2 isoform 1. | 0.494 |
| HRAS | MAPK3 | ENSPPYP00000003333 | ENSPPYP00000008184 | HRas proto-oncogene, GTPase. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.955 |
| HRAS | NRAS | ENSPPYP00000003333 | ENSPPYP00000001163 | HRas proto-oncogene, GTPase. | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | 0.997 |
| HRAS | RPS6KA1 | ENSPPYP00000003333 | ENSPPYP00000001941 | HRas proto-oncogene, GTPase. | Ribosomal protein S6 kinase. | 0.916 |
| HRAS | RPS6KA6 | ENSPPYP00000003333 | ENSPPYP00000022960 | HRas proto-oncogene, GTPase. | Ribosomal protein S6 kinase. | 0.908 |
| HRAS | TSC2 | ENSPPYP00000003333 | ENSPPYP00000007907 | HRas proto-oncogene, GTPase. | TSC2 isoform 1. | 0.505 |
| MAPK3 | ATF4 | ENSPPYP00000008184 | ENSPPYP00000013213 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | ATF4 isoform 1. | 0.915 |
| MAPK3 | ESR1 | ENSPPYP00000008184 | ENSPPYP00000019159 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.977 |
