PLP1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CR201_G0032376	PLP1	ENSPPYP00000014755	ENSPPYP00000023045	RESP18 isoform 1.	Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin (By similarity).	0.752
GRM7	PLP1	ENSPPYP00000015309	ENSPPYP00000023045	Metabotropic glutamate receptor 7; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity).	Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin (By similarity).	0.763
MAG	MBP	ENSPPYP00000011036	ENSPPYP00000010383	MAG isoform 1.	MBP isoform 10.	0.907
MAG	MOG	ENSPPYP00000011036	ENSPPYP00000018325	MAG isoform 1.	Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion (By similarity).	0.947
MAG	PLP1	ENSPPYP00000011036	ENSPPYP00000023045	MAG isoform 1.	Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin (By similarity).	0.945
MAG	SLC1A2	ENSPPYP00000011036	ENSPPYP00000003853	MAG isoform 1.	Amino acid transporter.	0.600
MAG	SYP	ENSPPYP00000011036	ENSPPYP00000022767	MAG isoform 1.	SYP isoform 1.	0.761
MAG	TNR	ENSPPYP00000011036	ENSPPYP00000000555	MAG isoform 1.	TNR isoform 1.	0.582
MBP	MAG	ENSPPYP00000010383	ENSPPYP00000011036	MBP isoform 10.	MAG isoform 1.	0.907
MBP	MOG	ENSPPYP00000010383	ENSPPYP00000018325	MBP isoform 10.	Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion (By similarity).	0.777
MBP	PLP1	ENSPPYP00000010383	ENSPPYP00000023045	MBP isoform 10.	Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin (By similarity).	0.979
MBP	SYP	ENSPPYP00000010383	ENSPPYP00000022767	MBP isoform 10.	SYP isoform 1.	0.530
MBP	TNR	ENSPPYP00000010383	ENSPPYP00000000555	MBP isoform 10.	TNR isoform 1.	0.404
MOG	MAG	ENSPPYP00000018325	ENSPPYP00000011036	Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion (By similarity).	MAG isoform 1.	0.947
MOG	MBP	ENSPPYP00000018325	ENSPPYP00000010383	Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion (By similarity).	MBP isoform 10.	0.777
MOG	PLP1	ENSPPYP00000018325	ENSPPYP00000023045	Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion (By similarity).	Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin (By similarity).	0.929
MOG	SLC1A2	ENSPPYP00000018325	ENSPPYP00000003853	Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion (By similarity).	Amino acid transporter.	0.639
MOG	SYP	ENSPPYP00000018325	ENSPPYP00000022767	Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion (By similarity).	SYP isoform 1.	0.581
MOG	TNR	ENSPPYP00000018325	ENSPPYP00000000555	Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion (By similarity).	TNR isoform 1.	0.527
PLP1	CR201_G0032376	ENSPPYP00000023045	ENSPPYP00000014755	Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin (By similarity).	RESP18 isoform 1.	0.752