| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EIF4A3 | MTREX | ENSPPYP00000009779 | ENSPPYP00000017285 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | SKIV2L2 isoform 1. | 0.851 |
| EIF4A3 | NCBP1 | ENSPPYP00000009779 | ENSPPYP00000021769 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | Nuclear cap binding protein subunit 1. | 0.938 |
| EIF4A3 | NCBP2 | ENSPPYP00000009779 | ENSPPYP00000016158 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.923 |
| EIF4A3 | NCBP2L | ENSPPYP00000009779 | ENSPPYP00000023075 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.904 |
| EIF4A3 | NELFE | ENSPPYP00000009779 | ENSPPYP00000018418 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | Negative elongation factor complex member E. | 0.433 |
| EIF4A3 | RBM8A | ENSPPYP00000009779 | ENSPPYP00000001082 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. | 0.991 |
| EIF4A3 | SRRT | ENSPPYP00000009779 | ENSPPYP00000019542 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | Serrate RNA effector molecule homolog; Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. [...] | 0.788 |
| EIF4A3 | UPF1 | ENSPPYP00000009779 | ENSPPYP00000010923 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | UPF1 isoform 2. | 0.991 |
| MTREX | EIF4A3 | ENSPPYP00000017285 | ENSPPYP00000009779 | SKIV2L2 isoform 1. | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | 0.851 |
| MTREX | NCBP1 | ENSPPYP00000017285 | ENSPPYP00000021769 | SKIV2L2 isoform 1. | Nuclear cap binding protein subunit 1. | 0.956 |
| MTREX | NCBP2 | ENSPPYP00000017285 | ENSPPYP00000016158 | SKIV2L2 isoform 1. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.918 |
| MTREX | NCBP2L | ENSPPYP00000017285 | ENSPPYP00000023075 | SKIV2L2 isoform 1. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.902 |
| MTREX | SRRT | ENSPPYP00000017285 | ENSPPYP00000019542 | SKIV2L2 isoform 1. | Serrate RNA effector molecule homolog; Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. [...] | 0.969 |
| MTREX | UPF1 | ENSPPYP00000017285 | ENSPPYP00000010923 | SKIV2L2 isoform 1. | UPF1 isoform 2. | 0.471 |
| MTREX | ZCCHC8 | ENSPPYP00000017285 | ENSPPYP00000005774 | SKIV2L2 isoform 1. | Zinc finger CCHC domain-containing protein 8; Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. May be involved in pre-mRNA splicing. | 0.989 |
| NCBP1 | EIF4A3 | ENSPPYP00000021769 | ENSPPYP00000009779 | Nuclear cap binding protein subunit 1. | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. | 0.938 |
| NCBP1 | MTREX | ENSPPYP00000021769 | ENSPPYP00000017285 | Nuclear cap binding protein subunit 1. | SKIV2L2 isoform 1. | 0.956 |
| NCBP1 | NCBP2 | ENSPPYP00000021769 | ENSPPYP00000016158 | Nuclear cap binding protein subunit 1. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.999 |
| NCBP1 | NCBP2L | ENSPPYP00000021769 | ENSPPYP00000023075 | Nuclear cap binding protein subunit 1. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.997 |
| NCBP1 | NELFE | ENSPPYP00000021769 | ENSPPYP00000018418 | Nuclear cap binding protein subunit 1. | Negative elongation factor complex member E. | 0.968 |
