Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MID2MID2 isoform 2. (705 aa)    
Predicted Functional Partners:
MID1
MID1 isoform 10.
    
   0.915
IGBP1
Immunoglobulin binding protein 1.
    
 
 0.851
UBE2D1
Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.
   
  0.714
UBE2D4
UBE2D4 isoform 3; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.713
SYT17
Synaptotagmin-17; Plays a role in dendrite formation by melanocytes. Belongs to the synaptotagmin family.
    
  0.630
DMPK
DM1 protein kinase.
   
 0.617
PTPA
Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
    
 
 0.589
EPN3
EPN3 isoform 1.
   
  0.580
LNX1
LNX1 isoform 2.
    
 
 0.559
PPP2CB
Serine/threonine-protein phosphatase.
    
 
 0.518
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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