| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARIH1 | CR201_G0048720 | ENSPPYP00000007505 | ENSPPYP00000023227 | RBR-type E3 ubiquitin transferase. | TOMM40 isoform 6. | 0.903 |
| ARIH1 | PINK1 | ENSPPYP00000007505 | ENSPPYP00000002052 | RBR-type E3 ubiquitin transferase. | PTEN induced kinase 1. | 0.918 |
| ARIH1 | TOMM20 | ENSPPYP00000007505 | ENSPPYP00000000099 | RBR-type E3 ubiquitin transferase. | Mitochondrial import receptor subunit TOM20 homolog; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases. Belongs to the Tom20 family. | 0.910 |
| ARIH1 | TOMM20L | ENSPPYP00000007505 | ENSPPYP00000006655 | RBR-type E3 ubiquitin transferase. | TOMM20L isoform 1. | 0.908 |
| ARIH1 | TOMM7 | ENSPPYP00000007505 | ENSPPYP00000019883 | RBR-type E3 ubiquitin transferase. | TOMM7 isoform 1. | 0.900 |
| ARIH1 | TOMM70 | ENSPPYP00000007505 | ENSPPYP00000015206 | RBR-type E3 ubiquitin transferase. | Translocase of outer mitochondrial membrane 70. | 0.901 |
| BECN1 | CR201_G0048720 | ENSPPYP00000009414 | ENSPPYP00000023227 | Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...] | TOMM40 isoform 6. | 0.903 |
| BECN1 | PINK1 | ENSPPYP00000009414 | ENSPPYP00000002052 | Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...] | PTEN induced kinase 1. | 0.950 |
| BECN1 | TOMM20 | ENSPPYP00000009414 | ENSPPYP00000000099 | Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...] | Mitochondrial import receptor subunit TOM20 homolog; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases. Belongs to the Tom20 family. | 0.923 |
| BECN1 | TOMM20L | ENSPPYP00000009414 | ENSPPYP00000006655 | Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...] | TOMM20L isoform 1. | 0.909 |
| BECN1 | TOMM7 | ENSPPYP00000009414 | ENSPPYP00000019883 | Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...] | TOMM7 isoform 1. | 0.900 |
| BECN1 | TOMM70 | ENSPPYP00000009414 | ENSPPYP00000015206 | Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...] | Translocase of outer mitochondrial membrane 70. | 0.903 |
| CR201_G0048720 | ARIH1 | ENSPPYP00000023227 | ENSPPYP00000007505 | TOMM40 isoform 6. | RBR-type E3 ubiquitin transferase. | 0.903 |
| CR201_G0048720 | BECN1 | ENSPPYP00000023227 | ENSPPYP00000009414 | TOMM40 isoform 6. | Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...] | 0.903 |
| CR201_G0048720 | PINK1 | ENSPPYP00000023227 | ENSPPYP00000002052 | TOMM40 isoform 6. | PTEN induced kinase 1. | 0.963 |
| CR201_G0048720 | SIAH1 | ENSPPYP00000023227 | ENSPPYP00000008278 | TOMM40 isoform 6. | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.903 |
| CR201_G0048720 | TOMM20 | ENSPPYP00000023227 | ENSPPYP00000000099 | TOMM40 isoform 6. | Mitochondrial import receptor subunit TOM20 homolog; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases. Belongs to the Tom20 family. | 0.989 |
| CR201_G0048720 | TOMM20L | ENSPPYP00000023227 | ENSPPYP00000006655 | TOMM40 isoform 6. | TOMM20L isoform 1. | 0.970 |
| CR201_G0048720 | TOMM22 | ENSPPYP00000023227 | ENSPPYP00000013190 | TOMM40 isoform 6. | Translocase of outer mitochondrial membrane 22. | 0.977 |
| CR201_G0048720 | TOMM5 | ENSPPYP00000023227 | ENSPPYP00000021359 | TOMM40 isoform 6. | Mitochondrial import receptor subunit TOM5 homolog; Belongs to the Tom5 family. | 0.915 |
