STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HTATSF1HIV Tat-specific factor 1 homolog; Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation (By similarity); Belongs to the HTATSF1 family. (756 aa)    
Predicted Functional Partners:
SF3B2
SF3B2 isoform 4.
   
 
 0.915
SF3B1
SF3B1 isoform 1.
    
 
 0.911
SF3A2
SF3A2 isoform 1.
   
 
 0.906
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
    
 
 0.897
SF3B6
Splicing factor 3b subunit 6.
    
 
 0.889
PHF5A
PHD finger protein 5A.
    
 
 0.883
SNRPB2
Small nuclear ribonucleoprotein polypeptide B2.
    
 
 0.875
SNRPF
Small nuclear ribonucleoprotein polypeptide F.
   
   0.867
SNRPD2
Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome.
    
 
 0.866
DDX46
Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation.
   
 0.852
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.