STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZIC3Zic family member 3. (466 aa)    
Predicted Functional Partners:
LOC100432049
NANOG isoform 2.
    
 0.745
ENSPPYP00000005886
annotation not available
    
 0.745
ACVR2B
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.699
SOX2
SRY-box transcription factor 2.
   
 0.691
NODAL
Nodal growth differentiation factor.
      
 0.687
LEFTY2
Left-right determination factor.
      
 0.686
GPR31
G protein-coupled receptor 31; Belongs to the G-protein coupled receptor 1 family.
      
 0.671
TDGF1
TDGF1 isoform 2.
    
 0.645
CR201_G0051763
CFC1B isoform 1.
    
 0.615
POU5F1
POU domain protein.
    
 0.613
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.