F9 protein (Pongo abelii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPA1	F9	ENSPPYP00000020200	ENSPPYP00000023262	Carboxypeptidase A1.	F9 isoform 2.	0.719
F10	F2	ENSPPYP00000006293	ENSPPYP00000003807	Coagulation factor X.	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	0.979
F10	F3	ENSPPYP00000006293	ENSPPYP00000001318	Coagulation factor X.	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	0.954
F10	F5	ENSPPYP00000006293	ENSPPYP00000000617	Coagulation factor X.	F5 isoform 3; Belongs to the multicopper oxidase family.	0.965
F10	F7	ENSPPYP00000006293	ENSPPYP00000006292	Coagulation factor X.	F7 isoform 3.	0.962
F10	F8	ENSPPYP00000006293	ENSPPYP00000023391	Coagulation factor X.	F8 isoform 2; Belongs to the multicopper oxidase family.	0.930
F10	F9	ENSPPYP00000006293	ENSPPYP00000023262	Coagulation factor X.	F9 isoform 2.	0.809
F10	GGCX	ENSPPYP00000006293	ENSPPYP00000013637	Coagulation factor X.	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.	0.939
F10	SERPINC1	ENSPPYP00000006293	ENSPPYP00000000566	Coagulation factor X.	Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity).	0.933
F10	TFPI	ENSPPYP00000006293	ENSPPYP00000014535	Coagulation factor X.	Tissue factor pathway inhibitor.	0.965
F2	F10	ENSPPYP00000003807	ENSPPYP00000006293	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Coagulation factor X.	0.979
F2	F3	ENSPPYP00000003807	ENSPPYP00000001318	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	0.866
F2	F5	ENSPPYP00000003807	ENSPPYP00000000617	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	F5 isoform 3; Belongs to the multicopper oxidase family.	0.984
F2	F7	ENSPPYP00000003807	ENSPPYP00000006292	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	F7 isoform 3.	0.737
F2	F8	ENSPPYP00000003807	ENSPPYP00000023391	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	F8 isoform 2; Belongs to the multicopper oxidase family.	0.958
F2	F9	ENSPPYP00000003807	ENSPPYP00000023262	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	F9 isoform 2.	0.767
F2	GGCX	ENSPPYP00000003807	ENSPPYP00000013637	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.	0.961
F2	SERPINC1	ENSPPYP00000003807	ENSPPYP00000000566	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity).	0.999
F2	TFPI	ENSPPYP00000003807	ENSPPYP00000014535	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Tissue factor pathway inhibitor.	0.710
F3	F10	ENSPPYP00000001318	ENSPPYP00000006293	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	Coagulation factor X.	0.954