| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAPRIN1 | FMR1 | ENSPPYP00000024685 | ENSPPYP00000023279 | CAPRIN1 isoform 1. | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | 0.831 |
| CAPRIN1 | FXR1 | ENSPPYP00000024685 | ENSPPYP00000016024 | CAPRIN1 isoform 1. | FMR1 autosomal homolog 1. | 0.933 |
| CAPRIN1 | FXR2 | ENSPPYP00000024685 | ENSPPYP00000008919 | CAPRIN1 isoform 1. | FXR2 isoform 2. | 0.900 |
| CAPRIN1 | G3BP1 | ENSPPYP00000024685 | ENSPPYP00000017869 | CAPRIN1 isoform 1. | Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RN [...] | 0.972 |
| CAPRIN1 | NUFIP2 | ENSPPYP00000024685 | ENSPPYP00000009131 | CAPRIN1 isoform 1. | NUFIP2 isoform 1. | 0.773 |
| CAPRIN1 | SERBP1 | ENSPPYP00000024685 | ENSPPYP00000001462 | CAPRIN1 isoform 1. | SERBP1 isoform 3. | 0.589 |
| CAPRIN1 | UBAP2L | ENSPPYP00000024685 | ENSPPYP00000000913 | CAPRIN1 isoform 1. | UBAP2L isoform 10. | 0.705 |
| CYFIP1 | FMR1 | ENSPPYP00000007096 | ENSPPYP00000023279 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | 0.839 |
| CYFIP1 | FXR1 | ENSPPYP00000007096 | ENSPPYP00000016024 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | FMR1 autosomal homolog 1. | 0.726 |
| CYFIP1 | FXR2 | ENSPPYP00000007096 | ENSPPYP00000008919 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | FXR2 isoform 2. | 0.755 |
| FMR1 | CAPRIN1 | ENSPPYP00000023279 | ENSPPYP00000024685 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | CAPRIN1 isoform 1. | 0.831 |
| FMR1 | CYFIP1 | ENSPPYP00000023279 | ENSPPYP00000007096 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | 0.839 |
| FMR1 | FXR1 | ENSPPYP00000023279 | ENSPPYP00000016024 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | FMR1 autosomal homolog 1. | 0.942 |
| FMR1 | FXR2 | ENSPPYP00000023279 | ENSPPYP00000008919 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | FXR2 isoform 2. | 0.945 |
| FMR1 | G3BP1 | ENSPPYP00000023279 | ENSPPYP00000017869 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RN [...] | 0.856 |
| FMR1 | NUFIP2 | ENSPPYP00000023279 | ENSPPYP00000009131 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | NUFIP2 isoform 1. | 0.887 |
| FMR1 | SERBP1 | ENSPPYP00000023279 | ENSPPYP00000001462 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | SERBP1 isoform 3. | 0.838 |
| FMR1 | SMN1 | ENSPPYP00000023279 | ENSPPYP00000017360 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | Survival motor neuron protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the ch [...] | 0.928 |
| FMR1 | TDRD3 | ENSPPYP00000023279 | ENSPPYP00000006153 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | TDRD3 isoform 1. | 0.930 |
| FMR1 | UBAP2L | ENSPPYP00000023279 | ENSPPYP00000000913 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | UBAP2L isoform 10. | 0.844 |
