node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDH18A1 | ASL | ENSPPYP00000002911 | ENSPPYP00000019643 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Argininosuccinate lyase isoform X1. | 0.727 |
ALDH18A1 | CYB5R4 | ENSPPYP00000002911 | ENSPPYP00000018819 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Cytochrome b5 reductase 4. | 0.504 |
ALDH18A1 | GART | ENSPPYP00000002911 | ENSPPYP00000012701 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.776 |
ALDH18A1 | GPR143 | ENSPPYP00000002911 | ENSPPYP00000023656 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | GPR143 isoform 1. | 0.801 |
ALDH18A1 | OTC | ENSPPYP00000002911 | ENSPPYP00000022656 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.551 |
ALDH18A1 | UMPS | ENSPPYP00000002911 | ENSPPYP00000015062 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family. | 0.586 |
ASL | ALDH18A1 | ENSPPYP00000019643 | ENSPPYP00000002911 | Argininosuccinate lyase isoform X1. | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.727 |
ASL | GART | ENSPPYP00000019643 | ENSPPYP00000012701 | Argininosuccinate lyase isoform X1. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.454 |
ASL | GPR143 | ENSPPYP00000019643 | ENSPPYP00000023656 | Argininosuccinate lyase isoform X1. | GPR143 isoform 1. | 0.725 |
ASL | OTC | ENSPPYP00000019643 | ENSPPYP00000022656 | Argininosuccinate lyase isoform X1. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.756 |
ASL | UMPS | ENSPPYP00000019643 | ENSPPYP00000015062 | Argininosuccinate lyase isoform X1. | Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family. | 0.523 |
CYB5R4 | ALDH18A1 | ENSPPYP00000018819 | ENSPPYP00000002911 | Cytochrome b5 reductase 4. | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.504 |
CYB5R4 | DHODH | ENSPPYP00000018819 | ENSPPYP00000008492 | Cytochrome b5 reductase 4. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | 0.882 |
CYB5R4 | DPYD | ENSPPYP00000018819 | ENSPPYP00000001308 | Cytochrome b5 reductase 4. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). | 0.881 |
CYB5R4 | GART | ENSPPYP00000018819 | ENSPPYP00000012701 | Cytochrome b5 reductase 4. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.529 |
CYB5R4 | GPR143 | ENSPPYP00000018819 | ENSPPYP00000023656 | Cytochrome b5 reductase 4. | GPR143 isoform 1. | 0.703 |
CYB5R4 | UMPS | ENSPPYP00000018819 | ENSPPYP00000015062 | Cytochrome b5 reductase 4. | Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family. | 0.915 |
DHODH | CYB5R4 | ENSPPYP00000008492 | ENSPPYP00000018819 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | Cytochrome b5 reductase 4. | 0.882 |
DHODH | GART | ENSPPYP00000008492 | ENSPPYP00000012701 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.766 |
DHODH | GPR143 | ENSPPYP00000008492 | ENSPPYP00000023656 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | GPR143 isoform 1. | 0.837 |