STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NESNES isoform 1; Belongs to the intermediate filament family. (1632 aa)    
Predicted Functional Partners:
GFAP
Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
    
 
0.831
CR201_G0005182
NEFM isoform 1; Belongs to the intermediate filament family.
    
0.778
SOX2
SRY-box transcription factor 2.
      
 0.758
DCX
DCX isoform 10.
      
 0.721
SYNM
SYNM isoform 4; Belongs to the intermediate filament family.
    
0.717
RBFOX3
RBFOX3 isoform 4.
    
 
 0.690
CDK5
Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.
    
 
 0.686
CR201_G0011084
CD44 isoform 1.
    
 
 0.682
PAX6
PAX6 isoform 13.
     
 0.670
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
      
 0.639
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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