STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC22CSEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family. (303 aa)    
Predicted Functional Partners:
BET1
BET1 isoform 1.
   
 0.935
STX5
STX5 isoform 1; Belongs to the syntaxin family.
   
 0.925
GOSR2
T0082108 isoform 1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
    
 0.877
YKT6
YKT6 v-SNARE homolog; Belongs to the synaptobrevin family.
    
 0.869
SCFD1
SCFD1 isoform 1; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.833
STX18
Syntaxin-18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
   
 0.831
BNIP1
BCL2 interacting protein 1.
   
 0.817
USE1
Unconventional SNARE in the endoplasmic reticulum protein 1.
    
 0.782
RINT1
RINT1 isoform 1.
    
 0.780
ZW10
Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (By similarity).
    
 0.776
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.