| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABAT | ALDH3B1 | ENSPPYP00000008008 | ENSPPYP00000003452 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.945 |
| ABAT | ALDH9A1 | ENSPPYP00000008008 | ENSPPYP00000000664 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | 0.945 |
| ABAT | CARNS1 | ENSPPYP00000008008 | ENSPPYP00000023856 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | CARNS1 isoform 6. | 0.910 |
| ABAT | CNDP2 | ENSPPYP00000008008 | ENSPPYP00000010372 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Cytosolic non-specific dipeptidase; Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Catalyzes the production of N- lactoyl-amino acids from lactate and amino acids by reverse proteolysis. | 0.934 |
| ABAT | GAD1 | ENSPPYP00000008008 | ENSPPYP00000014955 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. | 0.942 |
| ABAT | GADL1 | ENSPPYP00000008008 | ENSPPYP00000015717 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | GADL1 isoform 1. | 0.942 |
| ABAT | UPB1 | ENSPPYP00000008008 | ENSPPYP00000012992 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Beta-ureidopropionase; Catalyzes a late step in pyrimidine degradation. Converts N- carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta- aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide; Belongs to the carbon-nitrogen hydrolase superfamily. BUP family. | 0.941 |
| ALDH3B1 | ABAT | ENSPPYP00000003452 | ENSPPYP00000008008 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.945 |
| ALDH3B1 | CARNS1 | ENSPPYP00000003452 | ENSPPYP00000023856 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | CARNS1 isoform 6. | 0.904 |
| ALDH3B1 | CNDP2 | ENSPPYP00000003452 | ENSPPYP00000010372 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Cytosolic non-specific dipeptidase; Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Catalyzes the production of N- lactoyl-amino acids from lactate and amino acids by reverse proteolysis. | 0.908 |
| ALDH3B1 | GAD1 | ENSPPYP00000003452 | ENSPPYP00000014955 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. | 0.925 |
| ALDH3B1 | GADL1 | ENSPPYP00000003452 | ENSPPYP00000015717 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | GADL1 isoform 1. | 0.925 |
| ALDH3B1 | HDC | ENSPPYP00000003452 | ENSPPYP00000007330 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | HDC isoform 2. | 0.428 |
| ALDH3B1 | UPB1 | ENSPPYP00000003452 | ENSPPYP00000012992 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Beta-ureidopropionase; Catalyzes a late step in pyrimidine degradation. Converts N- carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta- aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide; Belongs to the carbon-nitrogen hydrolase superfamily. BUP family. | 0.918 |
| ALDH9A1 | ABAT | ENSPPYP00000000664 | ENSPPYP00000008008 | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.945 |
| ALDH9A1 | CARNS1 | ENSPPYP00000000664 | ENSPPYP00000023856 | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | CARNS1 isoform 6. | 0.904 |
| ALDH9A1 | CNDP2 | ENSPPYP00000000664 | ENSPPYP00000010372 | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | Cytosolic non-specific dipeptidase; Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Catalyzes the production of N- lactoyl-amino acids from lactate and amino acids by reverse proteolysis. | 0.913 |
| ALDH9A1 | GAD1 | ENSPPYP00000000664 | ENSPPYP00000014955 | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. | 0.922 |
| ALDH9A1 | GADL1 | ENSPPYP00000000664 | ENSPPYP00000015717 | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | GADL1 isoform 1. | 0.922 |
| ALDH9A1 | UPB1 | ENSPPYP00000000664 | ENSPPYP00000012992 | 4-trimethylaminobutyraldehyde dehydrogenase; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. | Beta-ureidopropionase; Catalyzes a late step in pyrimidine degradation. Converts N- carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta- aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide; Belongs to the carbon-nitrogen hydrolase superfamily. BUP family. | 0.920 |