| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSL | ATIC | ENSPPYP00000013221 | ENSPPYP00000014690 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | 0.999 |
| ADSL | ENSPPYP00000021704 | ENSPPYP00000013221 | ENSPPYP00000021704 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | annotation not available | 0.978 |
| ADSL | GART | ENSPPYP00000013221 | ENSPPYP00000012701 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ADSL | PAICS | ENSPPYP00000013221 | ENSPPYP00000016477 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily. | 0.997 |
| ADSL | PPAT | ENSPPYP00000013221 | ENSPPYP00000023924 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.977 |
| ADSL | PRPS1 | ENSPPYP00000013221 | ENSPPYP00000023072 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Ribose-phosphate pyrophosphokinase 1; Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis; Belongs to the ribose-phosphate pyrophosphokinase family. | 0.478 |
| ADSL | PRPS1L1 | ENSPPYP00000013221 | ENSPPYP00000019903 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosyl pyrophosphate synthetase 1 like 1. | 0.478 |
| ADSL | PRPS2 | ENSPPYP00000013221 | ENSPPYP00000022511 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Ribose-phosphate pyrophosphokinase 2; Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis; Belongs to the ribose-phosphate pyrophosphokinase family. | 0.478 |
| ATIC | ADSL | ENSPPYP00000014690 | ENSPPYP00000013221 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.999 |
| ATIC | ENSPPYP00000021704 | ENSPPYP00000014690 | ENSPPYP00000021704 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | annotation not available | 0.919 |
| ATIC | GART | ENSPPYP00000014690 | ENSPPYP00000012701 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ATIC | GLUL | ENSPPYP00000014690 | ENSPPYP00000000500 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Glutamine synthetase. | 0.673 |
| ATIC | PAICS | ENSPPYP00000014690 | ENSPPYP00000016477 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily. | 0.935 |
| ATIC | PPAT | ENSPPYP00000014690 | ENSPPYP00000023924 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.982 |
| CAD | GART | ENSPPYP00000014025 | ENSPPYP00000012701 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.750 |
| CAD | GLUL | ENSPPYP00000014025 | ENSPPYP00000000500 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamine synthetase. | 0.959 |
| CAD | PPAT | ENSPPYP00000014025 | ENSPPYP00000023924 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.971 |
| ENSPPYP00000021704 | ADSL | ENSPPYP00000021704 | ENSPPYP00000013221 | annotation not available | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.978 |
| ENSPPYP00000021704 | ATIC | ENSPPYP00000021704 | ENSPPYP00000014690 | annotation not available | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | 0.919 |
| ENSPPYP00000021704 | GART | ENSPPYP00000021704 | ENSPPYP00000012701 | annotation not available | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
