STEAP3 protein (Pongo abelii) - STRING interaction network

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Score

STEAP3

STEAP3 metalloreductase. (488 aa)

Predicted Functional Partners:

BNIP3L

0.963

FLVCR1

0.726

BNIP3

0.673

PKMYT1

0.640

FECH

0.638

SLC11A2

0.630

TP53

0.626

SNX27

0.622

SLC38A4

0.616

NRAS

0.590

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNIP3	BNIP3L	ENSPPYP00000003236	ENSPPYP00000020684	BNIP3 isoform 1.	BCL2 interacting protein 3 like.	0.876
BNIP3	STEAP3	ENSPPYP00000003236	ENSPPYP00000023979	BNIP3 isoform 1.	STEAP3 metalloreductase.	0.673
BNIP3	TP53	ENSPPYP00000003236	ENSPPYP00000008923	BNIP3 isoform 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.487
BNIP3L	BNIP3	ENSPPYP00000020684	ENSPPYP00000003236	BCL2 interacting protein 3 like.	BNIP3 isoform 1.	0.876
BNIP3L	PKMYT1	ENSPPYP00000020684	ENSPPYP00000007944	BCL2 interacting protein 3 like.	PKMYT1 isoform 10; Belongs to the protein kinase superfamily.	0.569
BNIP3L	STEAP3	ENSPPYP00000020684	ENSPPYP00000023979	BCL2 interacting protein 3 like.	STEAP3 metalloreductase.	0.963
BNIP3L	TP53	ENSPPYP00000020684	ENSPPYP00000008923	BCL2 interacting protein 3 like.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.529
FECH	FLVCR1	ENSPPYP00000010312	ENSPPYP00000000238	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Feline leukemia virus subgroup C cellular receptor 1.	0.723
FECH	STEAP3	ENSPPYP00000010312	ENSPPYP00000023979	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	STEAP3 metalloreductase.	0.638
FLVCR1	FECH	ENSPPYP00000000238	ENSPPYP00000010312	Feline leukemia virus subgroup C cellular receptor 1.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.723
FLVCR1	STEAP3	ENSPPYP00000000238	ENSPPYP00000023979	Feline leukemia virus subgroup C cellular receptor 1.	STEAP3 metalloreductase.	0.726
NRAS	STEAP3	ENSPPYP00000001163	ENSPPYP00000023979	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	STEAP3 metalloreductase.	0.590
NRAS	TP53	ENSPPYP00000001163	ENSPPYP00000008923	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.636
PKMYT1	BNIP3L	ENSPPYP00000007944	ENSPPYP00000020684	PKMYT1 isoform 10; Belongs to the protein kinase superfamily.	BCL2 interacting protein 3 like.	0.569
PKMYT1	STEAP3	ENSPPYP00000007944	ENSPPYP00000023979	PKMYT1 isoform 10; Belongs to the protein kinase superfamily.	STEAP3 metalloreductase.	0.640
SLC11A2	STEAP3	ENSPPYP00000024385	ENSPPYP00000023979	SLC11A2 isoform 12.	STEAP3 metalloreductase.	0.630
SLC38A4	STEAP3	ENSPPYP00000005067	ENSPPYP00000023979	Sodium-coupled neutral amino acid transporter 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by Ser, Gly, Cys, Asn, Thr, Pro and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH- dependent, with highest transport activity between pH 7.5 and 8.5 (By similarity).	STEAP3 metalloreductase.	0.616
SNX27	STEAP3	ENSPPYP00000001005	ENSPPYP00000023979	SNX27 isoform 2.	STEAP3 metalloreductase.	0.622
STEAP3	BNIP3	ENSPPYP00000023979	ENSPPYP00000003236	STEAP3 metalloreductase.	BNIP3 isoform 1.	0.673
STEAP3	BNIP3L	ENSPPYP00000023979	ENSPPYP00000020684	STEAP3 metalloreductase.	BCL2 interacting protein 3 like.	0.963