| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BAD | ENSPPYP00000024179 | ENSPPYP00000003594 | ENSPPYP00000024179 | BCL2 associated agonist of cell death. | 14-3-3 protein epsilon-like isoform X1. | 0.980 |
| BAD | YWHAB | ENSPPYP00000003594 | ENSPPYP00000012330 | BCL2 associated agonist of cell death. | 14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...] | 0.985 |
| BAD | YWHAG | ENSPPYP00000003594 | ENSPPYP00000019583 | BCL2 associated agonist of cell death. | 14-3-3 protein gamma, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. | 0.973 |
| BAD | YWHAH | ENSPPYP00000003594 | ENSPPYP00000013101 | BCL2 associated agonist of cell death. | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. | 0.985 |
| CDC25B | CDC25C | ENSPPYP00000012075 | ENSPPYP00000017694 | Cell division cycle 25B. | Cell division cycle 25C. | 0.962 |
| CDC25B | CSNK1D | ENSPPYP00000012075 | ENSPPYP00000009846 | Cell division cycle 25B. | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | 0.522 |
| CDC25B | ENSPPYP00000024179 | ENSPPYP00000012075 | ENSPPYP00000024179 | Cell division cycle 25B. | 14-3-3 protein epsilon-like isoform X1. | 0.983 |
| CDC25B | YWHAB | ENSPPYP00000012075 | ENSPPYP00000012330 | Cell division cycle 25B. | 14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...] | 0.995 |
| CDC25B | YWHAG | ENSPPYP00000012075 | ENSPPYP00000019583 | Cell division cycle 25B. | 14-3-3 protein gamma, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. | 0.984 |
| CDC25B | YWHAH | ENSPPYP00000012075 | ENSPPYP00000013101 | Cell division cycle 25B. | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. | 0.985 |
| CDC25C | CDC25B | ENSPPYP00000017694 | ENSPPYP00000012075 | Cell division cycle 25C. | Cell division cycle 25B. | 0.962 |
| CDC25C | CSNK1D | ENSPPYP00000017694 | ENSPPYP00000009846 | Cell division cycle 25C. | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | 0.539 |
| CDC25C | ENSPPYP00000024179 | ENSPPYP00000017694 | ENSPPYP00000024179 | Cell division cycle 25C. | 14-3-3 protein epsilon-like isoform X1. | 0.986 |
| CDC25C | YWHAB | ENSPPYP00000017694 | ENSPPYP00000012330 | Cell division cycle 25C. | 14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...] | 0.994 |
| CDC25C | YWHAG | ENSPPYP00000017694 | ENSPPYP00000019583 | Cell division cycle 25C. | 14-3-3 protein gamma, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. | 0.983 |
| CDC25C | YWHAH | ENSPPYP00000017694 | ENSPPYP00000013101 | Cell division cycle 25C. | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. | 0.984 |
| CSNK1D | CDC25B | ENSPPYP00000009846 | ENSPPYP00000012075 | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | Cell division cycle 25B. | 0.522 |
| CSNK1D | CDC25C | ENSPPYP00000009846 | ENSPPYP00000017694 | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | Cell division cycle 25C. | 0.539 |
| CSNK1D | ENSPPYP00000024179 | ENSPPYP00000009846 | ENSPPYP00000024179 | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | 14-3-3 protein epsilon-like isoform X1. | 0.937 |
| CSNK1D | WWTR1 | ENSPPYP00000009846 | ENSPPYP00000015879 | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | WW domain containing transcription regulator 1. | 0.914 |
