STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CR201_G0036243CD27 isoform 1. (159 aa)    
Predicted Functional Partners:
CD70
CD70 isoform 2; Belongs to the tumor necrosis factor family.
    
 0.997
CD86
CD86 isoform 2.
   
  
 0.829
CD80
CD80 isoform 4.
      
 0.820
TNFSF4
TNF superfamily member 4; Belongs to the tumor necrosis factor family.
      
 0.819
TNFSF9
TNFSF9 isoform 1; Belongs to the tumor necrosis factor family.
      
 0.817
SIVA1
Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
    
 
 0.787
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 
 0.748
CCR7
CCR7 isoform 1; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.740
CD5
CD5 isoform 1.
   
  
 0.738
CD19
CD19 isoform 3.
   
  
 0.732
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.