TMED2 protein (Pongo abelii) - STRING interaction network

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[Homology]

Score

TMED2

Transmembrane p24 trafficking protein 2. (208 aa)

Predicted Functional Partners:

TMED10

0.999

TMED4

0.979

TMED9

0.979

TMED3

0.974

TMED5

0.934

ENSPPYP00000016227

0.905

SURF4

0.905

SEC13

0.891

LMAN2

0.891

GORASP2

0.884

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPYP00000016227	GORASP2	ENSPPYP00000016227	ENSPPYP00000014426	annotation not available	GORASP2 isoform 1.	0.475
ENSPPYP00000016227	SURF4	ENSPPYP00000016227	ENSPPYP00000022130	annotation not available	Surfeit locus protein 4; May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi. Belongs to the SURF4 family.	0.796
ENSPPYP00000016227	TMED10	ENSPPYP00000016227	ENSPPYP00000024352	annotation not available	Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...]	0.921
ENSPPYP00000016227	TMED2	ENSPPYP00000016227	ENSPPYP00000024232	annotation not available	Transmembrane p24 trafficking protein 2.	0.905
ENSPPYP00000016227	TMED3	ENSPPYP00000016227	ENSPPYP00000007613	annotation not available	Transmembrane p24 trafficking protein 3.	0.709
ENSPPYP00000016227	TMED5	ENSPPYP00000016227	ENSPPYP00000001331	annotation not available	Transmembrane emp24 domain-containing protein 5; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport (By similarity).	0.582
GORASP2	ENSPPYP00000016227	ENSPPYP00000014426	ENSPPYP00000016227	GORASP2 isoform 1.	annotation not available	0.475
GORASP2	LMAN2	ENSPPYP00000014426	ENSPPYP00000018003	GORASP2 isoform 1.	Lectin, mannose binding 2.	0.475
GORASP2	SEC13	ENSPPYP00000014426	ENSPPYP00000015269	GORASP2 isoform 1.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.491
GORASP2	SURF4	ENSPPYP00000014426	ENSPPYP00000022130	GORASP2 isoform 1.	Surfeit locus protein 4; May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi. Belongs to the SURF4 family.	0.607
GORASP2	TMED10	ENSPPYP00000014426	ENSPPYP00000024352	GORASP2 isoform 1.	Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...]	0.738
GORASP2	TMED2	ENSPPYP00000014426	ENSPPYP00000024232	GORASP2 isoform 1.	Transmembrane p24 trafficking protein 2.	0.884
GORASP2	TMED3	ENSPPYP00000014426	ENSPPYP00000007613	GORASP2 isoform 1.	Transmembrane p24 trafficking protein 3.	0.484
GORASP2	TMED4	ENSPPYP00000014426	ENSPPYP00000019713	GORASP2 isoform 1.	Transmembrane p24 trafficking protein 4.	0.825
GORASP2	TMED9	ENSPPYP00000014426	ENSPPYP00000023555	GORASP2 isoform 1.	Transmembrane p24 trafficking protein 9.	0.708
LMAN2	GORASP2	ENSPPYP00000018003	ENSPPYP00000014426	Lectin, mannose binding 2.	GORASP2 isoform 1.	0.475
LMAN2	SEC13	ENSPPYP00000018003	ENSPPYP00000015269	Lectin, mannose binding 2.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.608
LMAN2	SURF4	ENSPPYP00000018003	ENSPPYP00000022130	Lectin, mannose binding 2.	Surfeit locus protein 4; May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi. Belongs to the SURF4 family.	0.557
LMAN2	TMED10	ENSPPYP00000018003	ENSPPYP00000024352	Lectin, mannose binding 2.	Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...]	0.850
LMAN2	TMED2	ENSPPYP00000018003	ENSPPYP00000024232	Lectin, mannose binding 2.	Transmembrane p24 trafficking protein 2.	0.891