PSMD4 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PSMD4

PSMD4 isoform 1. (384 aa)

Predicted Functional Partners:

PSMC3

0.999

PSMC6

0.999

PSMD11

0.999

PSMC4

0.999

ADRM1

0.999

PSMD14

0.999

PSMC2

0.999

PSMD7

0.999

PSMD5

0.998

PSMD12

0.997

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRM1	PSMC2	ENSPPYP00000012517	ENSPPYP00000020045	Adhesion regulating molecule 1.	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	0.984
ADRM1	PSMC3	ENSPPYP00000012517	ENSPPYP00000003790	Adhesion regulating molecule 1.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.983
ADRM1	PSMC4	ENSPPYP00000012517	ENSPPYP00000011174	Adhesion regulating molecule 1.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.994
ADRM1	PSMC6	ENSPPYP00000012517	ENSPPYP00000006612	Adhesion regulating molecule 1.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.977
ADRM1	PSMD11	ENSPPYP00000012517	ENSPPYP00000009176	Adhesion regulating molecule 1.	Proteasome 26S subunit, non-ATPase 11.	0.986
ADRM1	PSMD12	ENSPPYP00000012517	ENSPPYP00000009620	Adhesion regulating molecule 1.	26S proteasome non-ATPase regulatory subunit 12; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit p55 family.	0.987
ADRM1	PSMD14	ENSPPYP00000012517	ENSPPYP00000014374	Adhesion regulating molecule 1.	Proteasome 26S subunit, non-ATPase 14.	0.988
ADRM1	PSMD4	ENSPPYP00000012517	ENSPPYP00000024378	Adhesion regulating molecule 1.	PSMD4 isoform 1.	0.999
ADRM1	PSMD5	ENSPPYP00000012517	ENSPPYP00000021914	Adhesion regulating molecule 1.	PSMD5 isoform 8.	0.997
ADRM1	PSMD7	ENSPPYP00000012517	ENSPPYP00000023545	Adhesion regulating molecule 1.	PSMD7 isoform 1.	0.980
PSMC2	ADRM1	ENSPPYP00000020045	ENSPPYP00000012517	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	Adhesion regulating molecule 1.	0.984
PSMC2	PSMC3	ENSPPYP00000020045	ENSPPYP00000003790	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.999
PSMC2	PSMC4	ENSPPYP00000020045	ENSPPYP00000011174	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.999
PSMC2	PSMC6	ENSPPYP00000020045	ENSPPYP00000006612	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.999
PSMC2	PSMD11	ENSPPYP00000020045	ENSPPYP00000009176	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	Proteasome 26S subunit, non-ATPase 11.	0.997
PSMC2	PSMD12	ENSPPYP00000020045	ENSPPYP00000009620	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	26S proteasome non-ATPase regulatory subunit 12; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit p55 family.	0.999
PSMC2	PSMD14	ENSPPYP00000020045	ENSPPYP00000014374	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	Proteasome 26S subunit, non-ATPase 14.	0.999
PSMC2	PSMD4	ENSPPYP00000020045	ENSPPYP00000024378	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	PSMD4 isoform 1.	0.999
PSMC2	PSMD5	ENSPPYP00000020045	ENSPPYP00000021914	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	PSMD5 isoform 8.	0.994
PSMC2	PSMD7	ENSPPYP00000020045	ENSPPYP00000023545	26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...]	PSMD7 isoform 1.	0.998