RPTOR protein (Pongo abelii) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

RPTOR

RPTOR isoform 4. (708 aa)

Predicted Functional Partners:

RRAGC

0.999

MLST8

0.999

AKT1S1

0.999

RRAGD

0.999

RHEB

0.999

EIF4EBP1

0.999

RRAGA

0.999

RRAGB

0.999

LAMTOR5

0.998

LAMTOR1

0.998

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1S1	EIF4EBP1	ENSPPYP00000011493	ENSPPYP00000020757	AKT1S1 isoform 1.	Eukaryotic translation initiation factor 4E binding protein 1.	0.969
AKT1S1	LAMTOR1	ENSPPYP00000011493	ENSPPYP00000004168	AKT1S1 isoform 1.	Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...]	0.659
AKT1S1	LAMTOR5	ENSPPYP00000011493	ENSPPYP00000001218	AKT1S1 isoform 1.	LAMTOR5 isoform 1.	0.619
AKT1S1	MLST8	ENSPPYP00000011493	ENSPPYP00000007913	AKT1S1 isoform 1.	MTOR associated protein, LST8 homolog.	0.999
AKT1S1	RHEB	ENSPPYP00000011493	ENSPPYP00000020403	AKT1S1 isoform 1.	RHEB isoform 1.	0.987
AKT1S1	RPTOR	ENSPPYP00000011493	ENSPPYP00000024617	AKT1S1 isoform 1.	RPTOR isoform 4.	0.999
AKT1S1	RRAGA	ENSPPYP00000011493	ENSPPYP00000021503	AKT1S1 isoform 1.	Ras related GTP binding A.	0.992
AKT1S1	RRAGB	ENSPPYP00000011493	ENSPPYP00000022833	AKT1S1 isoform 1.	Ras related GTP binding B.	0.973
AKT1S1	RRAGC	ENSPPYP00000011493	ENSPPYP00000001752	AKT1S1 isoform 1.	RRAGC isoform 1.	0.990
AKT1S1	RRAGD	ENSPPYP00000011493	ENSPPYP00000018853	AKT1S1 isoform 1.	RRAGD isoform 1.	0.969
EIF4EBP1	AKT1S1	ENSPPYP00000020757	ENSPPYP00000011493	Eukaryotic translation initiation factor 4E binding protein 1.	AKT1S1 isoform 1.	0.969
EIF4EBP1	LAMTOR1	ENSPPYP00000020757	ENSPPYP00000004168	Eukaryotic translation initiation factor 4E binding protein 1.	Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...]	0.430
EIF4EBP1	MLST8	ENSPPYP00000020757	ENSPPYP00000007913	Eukaryotic translation initiation factor 4E binding protein 1.	MTOR associated protein, LST8 homolog.	0.996
EIF4EBP1	RHEB	ENSPPYP00000020757	ENSPPYP00000020403	Eukaryotic translation initiation factor 4E binding protein 1.	RHEB isoform 1.	0.931
EIF4EBP1	RPTOR	ENSPPYP00000020757	ENSPPYP00000024617	Eukaryotic translation initiation factor 4E binding protein 1.	RPTOR isoform 4.	0.999
EIF4EBP1	RRAGA	ENSPPYP00000020757	ENSPPYP00000021503	Eukaryotic translation initiation factor 4E binding protein 1.	Ras related GTP binding A.	0.572
EIF4EBP1	RRAGB	ENSPPYP00000020757	ENSPPYP00000022833	Eukaryotic translation initiation factor 4E binding protein 1.	Ras related GTP binding B.	0.562
EIF4EBP1	RRAGC	ENSPPYP00000020757	ENSPPYP00000001752	Eukaryotic translation initiation factor 4E binding protein 1.	RRAGC isoform 1.	0.633
EIF4EBP1	RRAGD	ENSPPYP00000020757	ENSPPYP00000018853	Eukaryotic translation initiation factor 4E binding protein 1.	RRAGD isoform 1.	0.601
LAMTOR1	AKT1S1	ENSPPYP00000004168	ENSPPYP00000011493	Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...]	AKT1S1 isoform 1.	0.659