node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC12 | FAM76A | ENSP00000292314 | ENSP00000010299 | Coiled-coil domain containing 12. | Protein FAM76A; Family with sequence similarity 76 member A. | 0.685 |
DYRK1B | FAM76A | ENSP00000469863 | ENSP00000010299 | Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. | Protein FAM76A; Family with sequence similarity 76 member A. | 0.488 |
ETFRF1 | FAM76A | ENSP00000450584 | ENSP00000010299 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | Protein FAM76A; Family with sequence similarity 76 member A. | 0.420 |
ETFRF1 | NPIPA7 | ENSP00000450584 | ENSP00000431814 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | Nuclear pore complex interacting protein family member A7. | 0.507 |
FAM76A | CCDC12 | ENSP00000010299 | ENSP00000292314 | Protein FAM76A; Family with sequence similarity 76 member A. | Coiled-coil domain containing 12. | 0.685 |
FAM76A | DYRK1B | ENSP00000010299 | ENSP00000469863 | Protein FAM76A; Family with sequence similarity 76 member A. | Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. | 0.488 |
FAM76A | ETFRF1 | ENSP00000010299 | ENSP00000450584 | Protein FAM76A; Family with sequence similarity 76 member A. | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | 0.420 |
FAM76A | MPDU1 | ENSP00000010299 | ENSP00000250124 | Protein FAM76A; Family with sequence similarity 76 member A. | Mannose-P-dolichol utilization defect 1 protein; Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors; Belongs to the MPDU1 (TC 2.A.43.3) family. | 0.446 |
FAM76A | NPIPA7 | ENSP00000010299 | ENSP00000431814 | Protein FAM76A; Family with sequence similarity 76 member A. | Nuclear pore complex interacting protein family member A7. | 0.655 |
FAM76A | NRBP1 | ENSP00000010299 | ENSP00000369192 | Protein FAM76A; Family with sequence similarity 76 member A. | Nuclear receptor-binding protein; May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.442 |
FAM76A | ODF3L2 | ENSP00000010299 | ENSP00000318029 | Protein FAM76A; Family with sequence similarity 76 member A. | Outer dense fiber of sperm tails 3 like 2. | 0.475 |
FAM76A | PPP1R8 | ENSP00000010299 | ENSP00000311677 | Protein FAM76A; Family with sequence similarity 76 member A. | Nuclear inhibitor of protein phosphatase 1; Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre- mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation. | 0.409 |
FAM76A | RBM42 | ENSP00000010299 | ENSP00000262633 | Protein FAM76A; Family with sequence similarity 76 member A. | RNA-binding protein 42; Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA. | 0.418 |
FAM76A | TMEM138 | ENSP00000010299 | ENSP00000278826 | Protein FAM76A; Family with sequence similarity 76 member A. | Transmembrane protein 138; Required for ciliogenesis. | 0.400 |
MPDU1 | FAM76A | ENSP00000250124 | ENSP00000010299 | Mannose-P-dolichol utilization defect 1 protein; Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors; Belongs to the MPDU1 (TC 2.A.43.3) family. | Protein FAM76A; Family with sequence similarity 76 member A. | 0.446 |
NPIPA7 | ETFRF1 | ENSP00000431814 | ENSP00000450584 | Nuclear pore complex interacting protein family member A7. | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family. | 0.507 |
NPIPA7 | FAM76A | ENSP00000431814 | ENSP00000010299 | Nuclear pore complex interacting protein family member A7. | Protein FAM76A; Family with sequence similarity 76 member A. | 0.655 |
NRBP1 | FAM76A | ENSP00000369192 | ENSP00000010299 | Nuclear receptor-binding protein; May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | Protein FAM76A; Family with sequence similarity 76 member A. | 0.442 |
ODF3L2 | FAM76A | ENSP00000318029 | ENSP00000010299 | Outer dense fiber of sperm tails 3 like 2. | Protein FAM76A; Family with sequence similarity 76 member A. | 0.475 |
PPP1R8 | FAM76A | ENSP00000311677 | ENSP00000010299 | Nuclear inhibitor of protein phosphatase 1; Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre- mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation. | Protein FAM76A; Family with sequence similarity 76 member A. | 0.409 |