STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPA1Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family (419 aa)    
Predicted Functional Partners:
CELA3B
Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity
   
 
 0.979
CELA3A
Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity
   
 
 0.969
CTRL
Chymotrypsin-like protease CTRL-1; Chymotrypsin like; Belongs to the peptidase S1 family
   
 
 0.961
CTRC
Chymotrypsin-C; Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity
   
 
 0.952
CTRB1
Chymotrypsinogen B1; Belongs to the peptidase S1 family
   
 
 0.945
CEL
Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family
   
  
 0.919
CTRB2
Chymotrypsinogen B2; Belongs to the peptidase S1 family
   
 
 0.918
CELA2A
Chymotrypsin-like elastase family member 2A; Acts upon elastin
   
 
 0.871
CPA2
M14 carboxypeptidases
  
 
0.867
CPB1
M14 carboxypeptidases; Belongs to the peptidase M14 family
  
  
0.844
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (8%) [HD]