node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAM7 | CRISP1 | ENSP00000175238 | ENSP00000338276 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | Cysteine-rich secretory protein 1; May have a role in sperm-egg fusion and maturation; Belongs to the CRISP family. | 0.418 |
ADAM7 | DCXR | ENSP00000175238 | ENSP00000303356 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | L-xylulose reductase; Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. | 0.487 |
ADAM7 | FN1 | ENSP00000175238 | ENSP00000346839 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. | 0.559 |
ADAM7 | GPX5 | ENSP00000175238 | ENSP00000392398 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | 0.456 |
ADAM7 | LCN8 | ENSP00000175238 | ENSP00000482512 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. | 0.443 |
ADAM7 | LCN9 | ENSP00000175238 | ENSP00000277526 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | Epididymal-specific lipocalin-9; Lipocalin 9. | 0.540 |
ADAM7 | TEDDM1 | ENSP00000175238 | ENSP00000356536 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | Transmembrane epididymal protein 1. | 0.472 |
ADAM7 | ZNF511 | ENSP00000175238 | ENSP00000355251 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | Zinc finger protein 511; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.496 |
CRISP1 | ADAM7 | ENSP00000338276 | ENSP00000175238 | Cysteine-rich secretory protein 1; May have a role in sperm-egg fusion and maturation; Belongs to the CRISP family. | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | 0.418 |
DCXR | ADAM7 | ENSP00000303356 | ENSP00000175238 | L-xylulose reductase; Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | 0.487 |
FN1 | ADAM7 | ENSP00000346839 | ENSP00000175238 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | 0.559 |
GPX5 | ADAM7 | ENSP00000392398 | ENSP00000175238 | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | 0.456 |
GPX5 | LCN8 | ENSP00000392398 | ENSP00000482512 | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. | 0.485 |
GPX5 | LCN9 | ENSP00000392398 | ENSP00000277526 | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | Epididymal-specific lipocalin-9; Lipocalin 9. | 0.633 |
LCN8 | ADAM7 | ENSP00000482512 | ENSP00000175238 | Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | 0.443 |
LCN8 | GPX5 | ENSP00000482512 | ENSP00000392398 | Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | 0.485 |
LCN8 | LCN9 | ENSP00000482512 | ENSP00000277526 | Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. | Epididymal-specific lipocalin-9; Lipocalin 9. | 0.894 |
LCN8 | TEDDM1 | ENSP00000482512 | ENSP00000356536 | Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. | Transmembrane epididymal protein 1. | 0.585 |
LCN9 | ADAM7 | ENSP00000277526 | ENSP00000175238 | Epididymal-specific lipocalin-9; Lipocalin 9. | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). | 0.540 |
LCN9 | GPX5 | ENSP00000277526 | ENSP00000392398 | Epididymal-specific lipocalin-9; Lipocalin 9. | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | 0.633 |