node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPA3 | TPSAB1 | ENSP00000296046 | ENSP00000343577 | Carboxypeptidase A3. | Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. | 0.945 |
CPA3 | TPSB2 | ENSP00000296046 | ENSP00000482743 | Carboxypeptidase A3. | Tryptase beta 2; Belongs to the peptidase S1 family. | 0.875 |
CPA3 | TPSD1 | ENSP00000296046 | ENSP00000211076 | Carboxypeptidase A3. | Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily. | 0.563 |
CPA4 | TPSAB1 | ENSP00000222482 | ENSP00000343577 | Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family. | Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. | 0.752 |
CPA4 | TPSB2 | ENSP00000222482 | ENSP00000482743 | Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family. | Tryptase beta 2; Belongs to the peptidase S1 family. | 0.663 |
CPA4 | TPSD1 | ENSP00000222482 | ENSP00000211076 | Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family. | Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily. | 0.496 |
TPSAB1 | CPA3 | ENSP00000343577 | ENSP00000296046 | Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. | Carboxypeptidase A3. | 0.945 |
TPSAB1 | CPA4 | ENSP00000343577 | ENSP00000222482 | Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. | Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family. | 0.752 |
TPSAB1 | TPSB2 | ENSP00000343577 | ENSP00000482743 | Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. | Tryptase beta 2; Belongs to the peptidase S1 family. | 0.999 |
TPSAB1 | TPSD1 | ENSP00000343577 | ENSP00000211076 | Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. | Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily. | 0.977 |
TPSB2 | CPA3 | ENSP00000482743 | ENSP00000296046 | Tryptase beta 2; Belongs to the peptidase S1 family. | Carboxypeptidase A3. | 0.875 |
TPSB2 | CPA4 | ENSP00000482743 | ENSP00000222482 | Tryptase beta 2; Belongs to the peptidase S1 family. | Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family. | 0.663 |
TPSB2 | TPSAB1 | ENSP00000482743 | ENSP00000343577 | Tryptase beta 2; Belongs to the peptidase S1 family. | Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. | 0.999 |
TPSB2 | TPSD1 | ENSP00000482743 | ENSP00000211076 | Tryptase beta 2; Belongs to the peptidase S1 family. | Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily. | 0.931 |
TPSD1 | CPA3 | ENSP00000211076 | ENSP00000296046 | Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily. | Carboxypeptidase A3. | 0.563 |
TPSD1 | CPA4 | ENSP00000211076 | ENSP00000222482 | Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily. | Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family. | 0.496 |
TPSD1 | TPSAB1 | ENSP00000211076 | ENSP00000343577 | Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily. | Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. | 0.977 |
TPSD1 | TPSB2 | ENSP00000211076 | ENSP00000482743 | Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily. | Tryptase beta 2; Belongs to the peptidase S1 family. | 0.931 |