TPSD1 protein (human) - STRING interaction network

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TPSD1

Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily. (242 aa)

Predicted Functional Partners:

TPSAB1

0.977

TPSB2

0.931

CPA3

0.563

CPA4

0.496

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPA3	TPSAB1	ENSP00000296046	ENSP00000343577	Carboxypeptidase A3.	Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.	0.945
CPA3	TPSB2	ENSP00000296046	ENSP00000482743	Carboxypeptidase A3.	Tryptase beta 2; Belongs to the peptidase S1 family.	0.875
CPA3	TPSD1	ENSP00000296046	ENSP00000211076	Carboxypeptidase A3.	Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.563
CPA4	TPSAB1	ENSP00000222482	ENSP00000343577	Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family.	Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.	0.752
CPA4	TPSB2	ENSP00000222482	ENSP00000482743	Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family.	Tryptase beta 2; Belongs to the peptidase S1 family.	0.663
CPA4	TPSD1	ENSP00000222482	ENSP00000211076	Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family.	Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.496
TPSAB1	CPA3	ENSP00000343577	ENSP00000296046	Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.	Carboxypeptidase A3.	0.945
TPSAB1	CPA4	ENSP00000343577	ENSP00000222482	Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.	Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family.	0.752
TPSAB1	TPSB2	ENSP00000343577	ENSP00000482743	Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.	Tryptase beta 2; Belongs to the peptidase S1 family.	0.999
TPSAB1	TPSD1	ENSP00000343577	ENSP00000211076	Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.	Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.977
TPSB2	CPA3	ENSP00000482743	ENSP00000296046	Tryptase beta 2; Belongs to the peptidase S1 family.	Carboxypeptidase A3.	0.875
TPSB2	CPA4	ENSP00000482743	ENSP00000222482	Tryptase beta 2; Belongs to the peptidase S1 family.	Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family.	0.663
TPSB2	TPSAB1	ENSP00000482743	ENSP00000343577	Tryptase beta 2; Belongs to the peptidase S1 family.	Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.	0.999
TPSB2	TPSD1	ENSP00000482743	ENSP00000211076	Tryptase beta 2; Belongs to the peptidase S1 family.	Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	0.931
TPSD1	CPA3	ENSP00000211076	ENSP00000296046	Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	Carboxypeptidase A3.	0.563
TPSD1	CPA4	ENSP00000211076	ENSP00000222482	Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	Carboxypeptidase A4; Metalloprotease that could be involved in the histone hyperacetylation pathway. Releases a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val ; Belongs to the peptidase M14 family.	0.496
TPSD1	TPSAB1	ENSP00000211076	ENSP00000343577	Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	Tryptase alpha/beta-1; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.	0.977
TPSD1	TPSB2	ENSP00000211076	ENSP00000482743	Tryptase delta; Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type; Belongs to the peptidase S1 family. Tryptase subfamily.	Tryptase beta 2; Belongs to the peptidase S1 family.	0.931

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