node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACBD6 | ASPHD2 | ENSP00000495710 | ENSP00000215906 | Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids. | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | 0.531 |
ACBD6 | B3GLCT | ENSP00000495710 | ENSP00000343002 | Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids. | Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. | 0.458 |
ACBD6 | TMEM53 | ENSP00000495710 | ENSP00000361311 | Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids. | Transmembrane protein 53; Belongs to the TMEM53 family. | 0.552 |
ASPHD2 | ACBD6 | ENSP00000215906 | ENSP00000495710 | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids. | 0.531 |
ASPHD2 | B3GLCT | ENSP00000215906 | ENSP00000343002 | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. | 0.467 |
ASPHD2 | FAM153B | ENSP00000215906 | ENSP00000427684 | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | Protein FAM153B; Family with sequence similarity 153 member B. | 0.447 |
ASPHD2 | FAM20B | ENSP00000215906 | ENSP00000263733 | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | Glycosaminoglycan xylosylkinase; Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O- phosphorylation may influence the catalyti [...] | 0.444 |
ASPHD2 | HPS4 | ENSP00000215906 | ENSP00000381213 | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | Hermansky-Pudlak syndrome 4 protein; Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38. | 0.462 |
ASPHD2 | SEZ6L | ENSP00000215906 | ENSP00000248933 | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | Seizure 6-like protein; May contribute to specialized endoplasmic reticulum functions in neurons. | 0.405 |
ASPHD2 | SRRD | ENSP00000215906 | ENSP00000215917 | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | SRR1-like protein; Plays a role in the regulation of heme biosynthesis and in the regulation of the expression of core clock genes. | 0.636 |
ASPHD2 | TMEM53 | ENSP00000215906 | ENSP00000361311 | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | Transmembrane protein 53; Belongs to the TMEM53 family. | 0.576 |
B3GLCT | ACBD6 | ENSP00000343002 | ENSP00000495710 | Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. | Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids. | 0.458 |
B3GLCT | ASPHD2 | ENSP00000343002 | ENSP00000215906 | Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | 0.467 |
B3GLCT | TMEM53 | ENSP00000343002 | ENSP00000361311 | Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan. | Transmembrane protein 53; Belongs to the TMEM53 family. | 0.490 |
FAM153B | ASPHD2 | ENSP00000427684 | ENSP00000215906 | Protein FAM153B; Family with sequence similarity 153 member B. | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | 0.447 |
FAM20B | ASPHD2 | ENSP00000263733 | ENSP00000215906 | Glycosaminoglycan xylosylkinase; Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O- phosphorylation may influence the catalyti [...] | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | 0.444 |
HPS4 | ASPHD2 | ENSP00000381213 | ENSP00000215906 | Hermansky-Pudlak syndrome 4 protein; Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38. | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | 0.462 |
SEZ6L | ASPHD2 | ENSP00000248933 | ENSP00000215906 | Seizure 6-like protein; May contribute to specialized endoplasmic reticulum functions in neurons. | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | 0.405 |
SEZ6L | SRRD | ENSP00000248933 | ENSP00000215917 | Seizure 6-like protein; May contribute to specialized endoplasmic reticulum functions in neurons. | SRR1-like protein; Plays a role in the regulation of heme biosynthesis and in the regulation of the expression of core clock genes. | 0.469 |
SRRD | ASPHD2 | ENSP00000215917 | ENSP00000215906 | SRR1-like protein; Plays a role in the regulation of heme biosynthesis and in the regulation of the expression of core clock genes. | Aspartate beta-hydroxylase domain-containing protein 2; May function as 2-oxoglutarate-dependent dioxygenase. | 0.636 |