Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C22orf31 | ESYT3 | ENSP00000216071 | ENSP00000374218 | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | Extended synaptotagmin-3; Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. | 0.497 |
| C22orf31 | HDAC2 | ENSP00000216071 | ENSP00000430432 | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S- phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed [...] | 0.601 |
| C22orf31 | KLHL20 | ENSP00000216071 | ENSP00000209884 | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | Kelch-like protein 20; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response and anterograde Golgi to endosome transport. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. The BCR(KLHL20) E3 ubiquitin ligase complex also specifically mediates 'Lys-33'-linked ubiquitination. Involved in anterograde Golgi to endosome transport by mediating 'Lys-33'-linked ubiquitination of CORO7, promoting inte [...] | 0.408 |
| C22orf31 | KRT33B | ENSP00000216071 | ENSP00000251646 | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | 0.450 |
| C22orf31 | LACRT | ENSP00000216071 | ENSP00000257867 | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | 0.468 |
| C22orf31 | LONRF3 | ENSP00000216071 | ENSP00000360690 | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | LON peptidase N-terminal domain and ring finger 3. | 0.447 |
| C22orf31 | TEDC1 | ENSP00000216071 | ENSP00000376307 | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | Tubulin epsilon and delta complex protein 1; Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability (By similarity). May play a role in counteracting perturbation of actin filaments, such as after treatment with the actin depolymerizing microbial metabolite Chivosazole F. | 0.541 |
| C22orf31 | TMED10 | ENSP00000216071 | ENSP00000303145 | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...] | 0.477 |
| C22orf31 | TP53I13 | ENSP00000216071 | ENSP00000301057 | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | Tumor protein p53-inducible protein 13; May act as a tumor suppressor. Inhibits tumor cell growth, when overexpressed. | 0.476 |
| ESYT3 | C22orf31 | ENSP00000374218 | ENSP00000216071 | Extended synaptotagmin-3; Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | 0.497 |
| HDAC2 | C22orf31 | ENSP00000430432 | ENSP00000216071 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S- phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed [...] | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | 0.601 |
| KLHL20 | C22orf31 | ENSP00000209884 | ENSP00000216071 | Kelch-like protein 20; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response and anterograde Golgi to endosome transport. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. The BCR(KLHL20) E3 ubiquitin ligase complex also specifically mediates 'Lys-33'-linked ubiquitination. Involved in anterograde Golgi to endosome transport by mediating 'Lys-33'-linked ubiquitination of CORO7, promoting inte [...] | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | 0.408 |
| KRT33B | C22orf31 | ENSP00000251646 | ENSP00000216071 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | 0.450 |
| LACRT | C22orf31 | ENSP00000257867 | ENSP00000216071 | Extracellular glycoprotein lacritin; Modulates secretion by lacrimal acinar cells. | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | 0.468 |
| LONRF3 | C22orf31 | ENSP00000360690 | ENSP00000216071 | LON peptidase N-terminal domain and ring finger 3. | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | 0.447 |
| TEDC1 | C22orf31 | ENSP00000376307 | ENSP00000216071 | Tubulin epsilon and delta complex protein 1; Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability (By similarity). May play a role in counteracting perturbation of actin filaments, such as after treatment with the actin depolymerizing microbial metabolite Chivosazole F. | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | 0.541 |
| TMED10 | C22orf31 | ENSP00000303145 | ENSP00000216071 | Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...] | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | 0.477 |
| TP53I13 | C22orf31 | ENSP00000301057 | ENSP00000216071 | Tumor protein p53-inducible protein 13; May act as a tumor suppressor. Inhibits tumor cell growth, when overexpressed. | Uncharacterized protein C22orf31; Chromosome 22 open reading frame 31. | 0.476 |